916525-77-4

Basic information

• Product Name: oxophenylacetic acid (1R,2S)-1,2-bis(2-methylphenyl)-2-(2-methylpropoxy)ethyl ester
• Synonyms: oxophenylacetic acid (1R,2S)-1,2-bis(2-methylphenyl)-2-(2-methylpropoxy)ethyl ester
• CAS NO: 916525-77-4
• Molecular Weight: 430.544
• Mol File: 916525-77-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: oxophenylacetic acid (1R,2S)-1,2-bis(2-methylphenyl)-2-(2-methylpropoxy)ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: oxophenylacetic acid (1R,2S)-1,2-bis(2-methylphenyl)-2-(2-methylpropoxy)ethyl ester(916525-77-4)
• EPA Substance Registry System: oxophenylacetic acid (1R,2S)-1,2-bis(2-methylphenyl)-2-(2-methylpropoxy)ethyl ester(916525-77-4)

Safety Data

• Hazardous Substances Data: 916525-77-4(Hazardous Substances Data)

Upstream product

• 529-20-4 2-methylphenyl aldehyde 
• 64158-25-4 meso-1,2-bis(2-methylphenyl)ethane-1,2-diol 
• 4389-39-3 2-hydroxy-1,2-bis(2-methylphenyl)ethanone 
• 916525-65-0 [1,2-bis(2-methylphenyl)-2-(2-methylpropoxy)ethoxy]-7,8,8-trimethyloctahydro-4,7-methanobenzo[b]furan 
• 916525-60-5 1,2-bis(2-methylphenyl)-2-[(7,8,8-trimethyloctahydro-4,7-methanobenzo[b]furan-2-yl)oxy]ethanol 
• 916525-72-9 (1R,2S)-1,2-bis(2-methylphenyl)-2-(2-methylpropoxy)ethanol 
• 611-73-4 Benzoylformic acid 

Downstream Products

• 916525-82-1 hydroxy(phenyl)acetic acid (1R,2S)-1,2-bis(2-methylphenyl)-2-(2-methylpropoxy)ethyl ester 

Relevant articles and documents

Chiral linker. Part 3: Synthesis and evaluation of aryl substituted m-hydrobenzoins as solid supported open chain chiral auxiliaries for the diastereoselective reduction of α-keto esters

Five partly novel aryl substituted m-hydrobenzoins were synthesized and the corresponding desymmetrized hydrobenzoin ethers evaluated as open chain chiral auxiliaries in the L-Selectride mediated stereoselective reduction of phenylglyoxylates, resulting in de values of up to 91%. Two optimized auxiliary structures were immobilized on commercially available Wang-resin and applied as a reusable solid supported chiral auxiliary in the same type of reaction.