916733-17-0

Basic information

• Product Name: (r)-1-acetyl-3-hydroxypyrrolidine
• Synonyms: (r)-1-acetyl-3-hydroxypyrrolidine;(r)-1-acetyl-3-pyrrolidinol;(r)-1-acetyl-3-hydroxypyr...;1-[(3R)-3-hydroxy-1-pyrrolidinyl]-Ethanone;1-[(3R)-3-hydroxypyrrolidin-1-yl]ethan-1-one;(R)-1-(3-Hydroxypyrrolidin-1-yl)ethanone;1-acetylpyrrolidin-3-ol;(R)-1-Acetyl-3-pyrrolidinol
• CAS NO: 916733-17-0
• Molecular Formula: C6H11NO2
• Molecular Weight: 129.16
• Product Categories: Chiral Building Blocks;Simple Alcohols (Chiral);Synthetic Organic Chemistry
• Mol File: 916733-17-0.mol
• Article Data: 3

Chemical Properties

• Melting Point: 83 °C
• Boiling Point: 286.417°C at 760 mmHg
• Flash Point: 127.021°C
• Appearance: /
• Density: 1.196g/cm³
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: -42 ° (C=3, MeOH)
• Storage Temp.: Sealed in dry,Room Temperature
• Solubility: soluble in Methanol
• PKA: 14.31±0.20(Predicted)
• CAS DataBase Reference: (r)-1-acetyl-3-hydroxypyrrolidine(CAS DataBase Reference)
• NIST Chemistry Reference: (r)-1-acetyl-3-hydroxypyrrolidine(916733-17-0)
• EPA Substance Registry System: (r)-1-acetyl-3-hydroxypyrrolidine(916733-17-0)

Safety Data

• Hazardous Substances Data: 916733-17-0(Hazardous Substances Data)

Usage

General Description

The chemical compound (r)-1-acetyl-3-hydroxypyrrolidine is a derivative of pyrrolidine, a five-membered heterogeneous nitrogen-containing hydrocarbon ring. It is a chiral molecule with a specific stereochemistry and is commonly used as an intermediate in the synthesis of pharmaceuticals and organic compounds. The acetyl group on the pyrrolidine ring gives it important chemical and biological properties, making it a valuable building block for the production of various drugs and other bioactive compounds. The hydroxypyrrolidine moiety in the molecule also contributes to its potential medicinal applications, as it can interact with biological systems and serve as a precursor for the synthesis of diverse bioactive molecules. Overall, (r)-1-acetyl-3-hydroxypyrrolidine is an important compound with versatile applications in chemical and pharmaceutical industries.

InChI:InChI=1/C6H11NO2/c1-5(8)7-3-2-6(9)4-7/h6,9H,2-4H2,1H3/t6-/m1/s1

Upstream product

• 40499-83-0 pyrrolidin-3-ol 
• 10387-40-3 potassium thioacetate 
• 40499-83-0 (3R)-pyrrolidinol 
• 75-36-5 acetyl chloride 

Relevant articles and documents

Potassium Thioacids Mediated Selective Amide and Peptide Constructions Enabled by Visible Light Photoredox Catalysis

A remarkable visible-light-promoted photoredox catalytic methodology involved with amines and eco-friendly potassium thioacids for amide formation was uncovered. This approach can mimic the natural coenzyme acetyl-CoA to selectively acylate amines without affecting other functional groups such as alcohols, phenols, esters, among others. The developed strategy may hold great potential for a comprehensive display of biologically interesting peptide synthesis and amino acid modification through a diacyl disulfide intermediate.

Aroylalkylpyrrolidines. Central nervous system depressants.

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