916792-63-7 Usage
General Description
2-ethyl 6-methyl-2,6dicarboxylate 1H-indole, also known as Vilazodone, is a chemical compound used as an antidepressant medication. It is a selective serotonin reuptake inhibitor and serotonin receptor partial agonist that works by increasing the levels of serotonin in the brain. Vilazodone is used to treat major depressive disorder in adults and is often prescribed in combination with therapy or other treatments. It is available in tablet form for oral administration and is generally well-tolerated, with common side effects including nausea, diarrhea, and insomnia. 2-ethyl 6-methyl-2,6dicarboxylate 1H-indole is an important tool in the treatment of depression and mood disorders.
Check Digit Verification of cas no
The CAS Registry Mumber 916792-63-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 9,1,6,7,9 and 2 respectively; the second part has 2 digits, 6 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 916792-63:
(8*9)+(7*1)+(6*6)+(5*7)+(4*9)+(3*2)+(2*6)+(1*3)=207
207 % 10 = 7
So 916792-63-7 is a valid CAS Registry Number.
916792-63-7Relevant articles and documents
Synthesis method for preparing 2-substituted indole derivative
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Paragraph 0211-0214, (2019/05/28)
The invention relates to a synthesis method for preparing a 2-substituted indole derivative. The method includes the following steps: mixing aromatic amine compounds (I), ketone compounds (II) and a drying agent in an organic solvent; adding a palladium catalyst; and reacting in an aerobic weak acid environment to prepare the indole compounds (III). (I), (II) and (III) are as shown in the specification, wherein R1 is selected from hydrogen, C1-C6 alkyl, C1-C6 alkoxy, C1-C6 alkanoyl, C2-C6 alkenyl, C2-C6 alkynyl, halogen, hydroxyl, substituted or unsubstituted amino, substituted or unsubstituted phenyl, pyridyl and heterocyclic aryl; (I) can be pyridylamine, pyrimidylamine, pyridazinam or pyrazinamide which may further be substituted or unsubstituted; and the substituents are selected fromone or more C1-C6 alkyl, C1-C6 alkoxy, C1-C6 alkanoyl, C2-C6 alkenyl, C2-C6 alkynyl, halogen, hydroxyl, amino; and R2 is selected from C1-C6 alkyl, formate groups or C1-C6 alkylamide groups.
