916824-56-1Relevant articles and documents
A Dichotomy in Cross-Coupling Site Selectivity in a Dihalogenated Heteroarene: Influence of Mononuclear Pd, Pd Clusters, and Pd Nanoparticles-The Case for Exploiting Pd Catalyst Speciation
Eyles, Anthony,Fairlamb, Ian J. S.,Ford, Mark J.,Jeddi, Neda,Scott, Neil W. J.,Simon, Lauriane,Tanner, Theo,Whitwood, Adrian C.,Willans, Charlotte E.
supporting information, p. 9682 - 9693 (2021/07/19)
Site-selective dihalogenated heteroarene cross-coupling with organometallic reagents usually occurs at the halogen proximal to the heteroatom, enabled by intrinsic relative electrophilicity, particularly in strongly polarized systems. An archetypical exam
Regioselectivity in alkenyl(aryl)-heteroaryl Suzuki cross-coupling reactions of 2,4-dibromopyridine. A?synthetic and mechanistic study
Sicre, Cristina,Alonso-Gómez, J.-Lorenzo,Cid, M. Magdalena
, p. 11063 - 11072 (2007/10/03)
2,4-Dibromopyridine undergoes a regioselective Suzuki cross-coupling reaction at position 2 with several alkenyl(aryl) boronic acids to render 4-bromo-2-carbon substituted pyridines, difficult to be prepared otherwise, in good yields under palladium catal