916907-68-1

Basic information

• Product Name: 1,1-Cyclopropanedicarboxylic acid, 2,2-dicyano-3-(4-methoxyphenyl)-, 1,1-dimethyl ester
• CAS NO: 916907-68-1
• Molecular Formula: C16H14N2O5
• Molecular Weight: 314.298
• Mol File: 916907-68-1.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: 1,1-Cyclopropanedicarboxylic acid, 2,2-dicyano-3-(4-methoxyphenyl)-, 1,1-dimethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 1,1-Cyclopropanedicarboxylic acid, 2,2-dicyano-3-(4-methoxyphenyl)-, 1,1-dimethyl ester(916907-68-1)
• EPA Substance Registry System: 1,1-Cyclopropanedicarboxylic acid, 2,2-dicyano-3-(4-methoxyphenyl)-, 1,1-dimethyl ester(916907-68-1)

Safety Data

• Hazardous Substances Data: 916907-68-1(Hazardous Substances Data)

Upstream product

• 2826-26-8 2-(4-methoxyphenylmethylene)malononitrile 
• 868-26-8 dimethyl 2-bromomalonate 
• 123-11-5 4-methoxy-benzaldehyde 
• 109-77-3 malononitrile 
• 108-59-8 malonic acid dimethyl ester 
• 37167-59-2 dimethyl dibromomalonate 

Relevant articles and documents

Synthesis of activated cyclopropanes by an MIRC strategy: An enantioselective organocatalytic approach to spirocyclopropanes

An efficient cyclopropanation, by a Michael-initiated ring-closing (MIRC) reaction of 2-arylidene-1,3-indandiones and 2-arylidene malononitriles, has been developed by using different α-monohalogenated methylene active compounds with triethylamine. The first enantioselective cyclopropanation to spirocyclopropanes derived by the reaction of 2-arylidene-1,3-indandiones and dimethyl bromomalonate with a commercially available α,α-L- diarylprolinol as the organocatalyst and K2CO3 as the additive has been accomplished. The spirocyclopropanes were isolated in high yield and up to 85% ee. Notably, the asymmetric one-pot sequential approach to spirocyclopropanes proved to be a feasible process. A simple triethylamine-promoted domino cyclopropanation of 2-arylidene-1,3-indandiones and 2-arylidenemalononitriles with α-monohalogenated methylene-active compounds has been efficiently developed. Spirocyclopropanes derived from 2-arylidene-1,3-indandiones were synthesized with up to 85% ee by using dimethyl bromomalonate and α,α-L-diarylprolinol/K2CO3 system. Copyright

Reaction of organozinc reagents formed in reaction of dibromomalonic acid dialkyl esters and zinc, with 2-arylmethylenemalonic acid dinitriles and 3-aryl-2-cyanopropenoic acid methyl esters

Organozinc compounds, obtained from dibromomalonic acid dialkyl esters and zinc, react with 2-arylmethylmalonic acid dinitriles and 3-aryl-2-cyanopropenoic acid methyl esters forming 3-aryl-2,2-dicyanocyclopropane-1,1-dicarboxylic acid dialkyl esters and

Electrocatalytic transformation of dialkyl malonates and arylidene- or alkylidenemalononitriles into dialkyl esters of 3-substituted 2,2-dicyanocyclopropane-1,1-dicarboxylic acids

Electrolysis of alcoholic solutions of dialkyl malonates and arylidene- or alkylidenemalononitriles in the presence of NaBr in an undivided cell gave dialkyl esters of 3-substituted 2,2-dicyanocyclopropane-1,1-dicarboxylic acids in 60-90% yields.