916917-28-7 Usage
Description
5,7,4'-Trihydroxy-8-Methylflavanone, also known as 5,7-Dihydroxy-2-(4-hydroxyphenyl)-8-methylchroman-4-one, is a phenolic derivative found in Qualea grandiflora and Qualea cordata plants. It is a flavanone compound characterized by the presence of three hydroxyl groups at the 5, 7, and 4' positions, as well as a methyl group at the 8 position. This unique structure endows it with potential biological activities and applications in various fields.
Uses
Used in Pharmaceutical Industry:
5,7,4'-Trihydroxy-8-Methylflavanone is used as a pharmaceutical agent for its potential therapeutic properties. The presence of multiple hydroxyl groups allows it to interact with various biological targets, making it a promising candidate for the development of new drugs. Its antioxidant, anti-inflammatory, and antimicrobial properties can be harnessed to treat a range of diseases and conditions.
Used in Cosmetic Industry:
In the cosmetic industry, 5,7,4'-Trihydroxy-8-Methylflavanone is used as an active ingredient for its skin-friendly properties. Its antioxidant and anti-inflammatory actions can help protect the skin from environmental stressors, reduce inflammation, and promote skin health. It can be incorporated into skincare products such as creams, lotions, and serums to provide these benefits to consumers.
Used in Food and Beverage Industry:
5,7,4'-Trihydroxy-8-Methylflavanone can be used in the food and beverage industry as a natural preservative and flavor enhancer. Its antioxidant properties can help extend the shelf life of food products by preventing oxidation and spoilage. Additionally, its unique structure may contribute to the development of new flavors and taste profiles in various food and beverage applications.
Used in Nutraceutical Industry:
As a nutraceutical, 5,7,4'-Trihydroxy-8-Methylflavanone can be used to promote overall health and well-being. Its potential health benefits, such as antioxidant and anti-inflammatory actions, can be incorporated into dietary supplements and functional foods to support immune function, cardiovascular health, and general wellness.
Used in Agricultural Industry:
In agriculture, 5,7,4'-Trihydroxy-8-Methylflavanone can be utilized as a natural pesticide or growth promoter. Its antimicrobial properties can help protect crops from diseases and pests, while its potential growth-promoting effects can contribute to increased crop yields and improved plant health. This can lead to more sustainable and environmentally friendly agricultural practices.
Check Digit Verification of cas no
The CAS Registry Mumber 916917-28-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 9,1,6,9,1 and 7 respectively; the second part has 2 digits, 2 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 916917-28:
(8*9)+(7*1)+(6*6)+(5*9)+(4*1)+(3*7)+(2*2)+(1*8)=197
197 % 10 = 7
So 916917-28-7 is a valid CAS Registry Number.
916917-28-7Relevant articles and documents
Subtle side-chain modifications of the hop phytoestrogen 8-prenylnaringenin result in distinct agonist/antagonist activity profiles for estrogen receptors α and β
Roelens, Frederik,Heldring, Nina,Dhooge, Willem,Bengtsson, Martin,Comhaire, Frank,Gustafsson, Jan-?ke,Treuter, Eckardt,De Keukeleire, Denis
, p. 7357 - 7365 (2007/10/03)
In search of therapeutic agents for estrogen-related pathologies, phytoestrogens are being extensively explored. In contrast to naringenin, 8-prenylnaringenin is a potent hop-derived estrogenic compound, highlighting the importance of the prenyl group for hormonal activity. We investigated the effects of substituting the prenyl group at C(8) with alkyl chains of varying lengths and branching patterns on estrogen receptor (ER) subtype ERα- and ERβ-binding affinities and transcriptional activities. In addition, features of the ligand-induced receptor conformations were explored using a set of specific ER-binding peptides. The new 8-alkylnaringenins were found to span an activity spectrum ranging from full agonism to partial agonism to antagonism. Most strikingly, 8-(2,2-dimethylpropyl)naringenin exhibited full agonist character on ERα, but pronounced antagonist character on ERβ. Knowledge on how ER-subtype-selective activities can be designed provides valuable information for future drug or tool compound discovery.
