916978-65-9

Basic information

• Product Name: 6-benzyloxy-6'-bromo-2-(diphenyl-phosphinoyl)-4-methoxy-2'-nitro-biphenyl
• Synonyms: 6-benzyloxy-6'-bromo-2-(diphenyl-phosphinoyl)-4-methoxy-2'-nitro-biphenyl
• CAS NO: 916978-65-9
• Molecular Weight: 614.432
• Mol File: 916978-65-9.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 6-benzyloxy-6'-bromo-2-(diphenyl-phosphinoyl)-4-methoxy-2'-nitro-biphenyl(CAS DataBase Reference)
• NIST Chemistry Reference: 6-benzyloxy-6'-bromo-2-(diphenyl-phosphinoyl)-4-methoxy-2'-nitro-biphenyl(916978-65-9)
• EPA Substance Registry System: 6-benzyloxy-6'-bromo-2-(diphenyl-phosphinoyl)-4-methoxy-2'-nitro-biphenyl(916978-65-9)

Safety Data

• Hazardous Substances Data: 916978-65-9(Hazardous Substances Data)

Upstream product

• 20357-21-5 2-bromo-6-nitrobenzaldehyde 
• 55289-35-5 2-bromo-6-nitrotoluene 
• 916978-62-6 6'-bromo-6-(diphenyl-phosphinoyl)-4-methoxy-2'-nitro-biphenyl-2-ol 
• 100-39-0 benzyl bromide 
• 1499-21-4 Diphenylphosphinic chloride 
• 105205-47-8 [(E)-2-(2-Bromo-6-nitro-phenyl)-vinyl]-dimethyl-amine 
• 916978-59-1 2-bromo-6-nitrophenylacetylene diphenylphosphine oxide 
• 916978-57-9 6-bromo-2-nitrophenylacetylene 

Relevant articles and documents

METHOD FOR MAKING BIARYL COMPOUNDS, COMPOUNDS MADE BY THE METHOD, AND METHOD FOR THEIR USE

Certain disclosed embodiments of the present invention concern a method for making biaryl compounds by combining a diene with a dienophile under reaction conditions that facilitate a Diels-Alder reaction. Certain embodiments are particularly directed to making a tetra-ortho-substituted biaryl compounds. The disclosed method may involve using novel dienes, dienophiles, or both. Similarly, certain of the biaryl compounds are novel compounds too. Additional disclosed embodiments concern a method for making useful compounds by first making a Diels-Alder adduct. The Diels-Alder adduct is then further modified or coupled to other compounds. The method can be used to make carbazoles, such as Siamenol. Disclosed biaryl compounds are useful for a number of applications, such as pharmacophores and organocatalysts.

Diels-Alder approach to polysubstituted biaryls: Rapid entry to tri- and tetra-ortho-substituted phosphorus-containing biaryls

Rapid construction: A Diels-Alder-based approach to the synthesis of highly functionalized biaryls from readily available precursors is disclosed. The utility of these biaryl templates in palladium-mediated couplings is explored along with subsequent redu