916979-34-5

Basic information

• Product Name: Allopurinol-d2
• Synonyms: 1,5-Dihydro-4H-pyrazolo[3,4-d]pyriMidin-4-one-d2;4-Hydroxypyrazolo[3,4-d]pyriMidine-d2;4-Oxopyrazolo[3,4-d]pyriMidine-d2;Adenock-d2;Allopur-d2;Caplenal-d2;Cellidrin-d2;NSC 101655-d2
• CAS NO: 916979-34-5
• Molecular Formula: C5H2D2N4O
• Molecular Weight: 138.123783556
• Product Categories: Pharmaceuticals;Bases & Related Reagents;Heterocycles;Intermediates & Fine Chemicals;Isotope Labelled Compounds;Nucleotides
• Mol File: 916979-34-5.mol
• Article Data: 0

Chemical Properties

• Melting Point: >358°C (dec.)
• Boiling Point: 463.5 °C at 760 mmHg
• Flash Point: 234.117 °C
• Appearance: /
• Density: 1.92 g/cm³
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.903
• Storage Temp.: Refrigerator, Under Inert Atmosphere
• CAS DataBase Reference: Allopurinol-d2(CAS DataBase Reference)
• NIST Chemistry Reference: Allopurinol-d2(916979-34-5)
• EPA Substance Registry System: Allopurinol-d2(916979-34-5)

Safety Data

• Hazardous Substances Data: 916979-34-5(Hazardous Substances Data)

Usage

Description

Allopurinol-d2 is a labeled xanthine oxidase inhibitor, which is a modified version of the drug Allopurinol. It is designed to help researchers study the drug's metabolism and mechanism of action in the body. Allopurinol-d2 works by reducing the production of uric acid, making it a valuable tool in the study of conditions related to elevated uric acid levels.

Uses

Used in Pharmaceutical Research:
Allopurinol-d2 is used as a research tool for studying the effects of xanthine oxidase inhibition on uric acid production. It helps researchers understand the drug's metabolism and mechanism of action, which can lead to the development of more effective treatments for hyperuricemia and gout.
Used in Treatment of Hyperuricemia:
Allopurinol-d2 is used as a therapeutic agent for the treatment of hyperuricemia, a condition characterized by abnormally high levels of uric acid in the blood. By decreasing uric acid production, it helps manage and prevent complications associated with this condition.
Used in Treatment of Chronic Gout:
Allopurinol-d2 is also used in the treatment of chronic gout, a form of arthritis caused by the accumulation of uric acid crystals in the joints. As a xanthine oxidase inhibitor, it reduces uric acid production, providing relief from the pain and inflammation associated with gout attacks and helping to prevent future episodes.

InChI:InChI=1/C5H4N4O/c10-5-3-1-8-9-4(3)6-2-7-5/h1-2H,(H2,6,7,8,9,10)/i1D,2D