916988-26-6

Basic information

• Product Name: 4-Methyl-benzoic acid 2-benzoyl-4-methyl-phenyl ester
• Synonyms: 4-Methyl-benzoic acid 2-benzoyl-4-methyl-phenyl ester
• CAS NO: 916988-26-6
• Molecular Weight: 330.383
• Mol File: 916988-26-6.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 4-Methyl-benzoic acid 2-benzoyl-4-methyl-phenyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 4-Methyl-benzoic acid 2-benzoyl-4-methyl-phenyl ester(916988-26-6)
• EPA Substance Registry System: 4-Methyl-benzoic acid 2-benzoyl-4-methyl-phenyl ester(916988-26-6)

Safety Data

• Hazardous Substances Data: 916988-26-6(Hazardous Substances Data)

Upstream product

• 614-34-6 p-cresyl benzoate 
• 1470-57-1 2-hydroxy-5-methylbenzophenone 
• 874-60-2 4-methyl-benzoyl chloride 
• 15024-08-5 4-methylphenyl 4-methylbenzoate 
• 98-88-4 benzoyl chloride 

Downstream Products

• 116544-55-9 (2-Benzoyl-4-methyl-phenoxy)-p-tolyl-acetic acid ethyl ester 
• 116544-65-1 (2-Benzoyl-4-methyl-phenoxy)-p-tolyl-acetic acid 
• 16762-24-6 2-(4-methylphenyl)-3-phenyl-5-methylbenzofuran 
• 1470-57-1 2-hydroxy-5-methylbenzophenone 
• 99-94-5 p-Toluic acid 

Relevant articles and documents

Synthesis and crystallographic analysis of benzophenone derivatives-The potential anti-inflammatory agents

Fries rearrangement of substituted phenyl benzoates 1a-j to substituted hydroxy benzophenones 2a-j was achieved in excellent yield. Further benzoylation of 2a-j to benzoyloxy benzophenones 4a-n, a benzophenone analogue was achieved in good yield. All the newly synthesized compounds were evaluated for their anti-inflammatory activity and were compared with standard drugs. Out of the compounds studied, the compounds 4c, 4e, 4g, 4h and 4k with chloro and methyl substituents at para position showed more potent activity than the standard drugs at all doses tested.