91703-34-3

Basic information

• Product Name: Phenol, 2-(2,2-dibromoethenyl)-
• CAS NO: 91703-34-3
• Molecular Formula: C8H6Br2O
• Molecular Weight: 277.943
• Mol File: 91703-34-3.mol
• Article Data: 12

Chemical Properties

• CAS DataBase Reference: Phenol, 2-(2,2-dibromoethenyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Phenol, 2-(2,2-dibromoethenyl)-(91703-34-3)
• EPA Substance Registry System: Phenol, 2-(2,2-dibromoethenyl)-(91703-34-3)

Safety Data

• Hazardous Substances Data: 91703-34-3(Hazardous Substances Data)

Upstream product

• 558-13-4 carbon tetrabromide 
• 90-02-8 salicylaldehyde 
• 90585-32-3 1,1-dibromo-2-(2-methoxyphenyl)ethene 
• 135-02-4 ortho-anisaldehyde 
• 42867-45-8 (dibromomethylene)triphenylphosphorane 
• 613-84-3 2-hydroxy-5-methylbenzaldehyde 

Downstream Products

• 271-89-6 1-benzofurane 
• 5101-44-0 2-ethynyl-phenol 
• 54008-77-4 2-bromo-1-benzofuran 
• 1309868-12-9 2-(benzofuran-2-yl)-5-(4-nitrophenyl)-oxazole 
• 1309868-11-8 2-(benzofuran-2-yl)-5-phenyloxazole 
• 94138-70-2 2-(benzofuran-2-yl)-5-phenyl-1,3,4-oxadiazole 
• 1309868-08-3 8-(benzofuran-2-yl)-7-benzyl-1,3-dimethylxanthine 
• 1309868-07-2 2-(benzofuran-2-yl)-5-(4-fluorophenyl)-oxazole 
• 1839-72-1 2-phenylbenzofuran 
• 1378942-55-2 2-(gem-dibromovinyl)phenol-d 
• 25664-48-6 2-p-tolyl-benzofuran 
• 39195-66-9 2-(4-chlorophenyl)benzofuran 
• 65246-40-4 2‐(4‐tert‐butylphenyl)benzofuran 
• 19234-04-9 2-(p-methoxyphenyl)-benzo[b]furan 

Relevant articles and documents

Palladium-Catalyzed Domino Cyclization/Phosphorylation of gem-Dibromoolefins with P(O)H Compounds: Synthesis of Phosphorylated Heteroaromatics

We presented a palladium-catalyzed domino cyclization/phosphorylation of gem-dibromoolefins, which utilize H-phosphinates and secondary phosphine oxides as the phosphine sources, respectively. A variety of phosphorylated heteroaromatics were obtained in m

Highly Efficient Synthesis of 2-Substituted Benzo[ b ]furan Derivatives from the Cross-Coupling Reactions of 2-Halobenzo[ b ]furans with Organoalane Reagents

A highly efficient and simple route for the synthesis of 2-substituted benzo[ b ]furans has been developed by palladium-catalyzed cross-coupling reaction of 2-halobenzo[ b ]furans with aryl, alkynyl, and alkylaluminum reagents. Various 2-aryl-, 2-alkynyl-, and 2-alkyl-substituted benzo[ b ]furan derivatives can be obtained in 23-97% isolated yields using 2-3 mol% PdCl 2/4-6 mol% XantPhos as the catalyst under mild reaction conditions. The aryls bearing electron-donating or electron-withdrawing groups in 2-halobenzo[ b ]furans gave products in 40-97% isolated yields. In addition, aluminum reagents containing thienyl, furanyl, trimethylsilanyl, and benzyl groups worked efficiently with 2-halobenzo[ b ]furans as well, and three bioactive molecules with 2-substituted benzo[ b ]furan skeleton were synthesized. Furthermore, the broad substrates scope and the typical maintenance of vigorous efficiency on gram scale make this protocol a potentially practical method to synthesize 2-substituted benzo[ b ]furan derivatives. On the basis of the experimental results, a possible catalytic cycle has been proposed.

Rapid Access to Benzofuran-Based Natural Products through a Concise Synthetic Strategy

A concise strategy is described for the synthesis of ailanthoidol (1), egonol (2), homoegonol (3), demethoxyegonol (4), demethoxyhomoegonol (5), and stemofuran A (6). This approach involves a Pd-catalysed domino cyclization/coupling process using triarylbismuth reagents for the generation of the benzofuran core. Subsequent structural modifications then give the final targets. The high yielding synthesis of the recently isolated natural products egonol-9(Z)-12(Z)-linoleate (2a), 7-demethoxyegonol-9(Z)-12(Z)-linoleate (4a), and 7-demethoxy-egonol-9(Z)-oleate (4b) are also reported.