91713-42-7Relevant articles and documents
4'-SUBSTITUTED NUCLEOSIDE REVERSE TRANSCRIPTASE INHIBITORS
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, (2015/12/08)
Provided is 4'-substituted nucleoside derivatives of Formula I and their use in the inhibition of HIV reverse transcriptase, the prophylaxis of infection by HIV, the treatment of infection by HIV, and the prophylaxis, treatment, and delay in the onset or progression of AIDS and/or ARC.
7-Deaza Isosters of 2'-Deoxyxanthosine and 2'-Deoxyspongosine - Synthesis via Glycosylation of 2,4-Dichloro-7H-pyrrolopyrimidine
Seela, Frank,Driller, Hansjuergen,Liman, Ulrich
, p. 312 - 320 (2007/10/02)
7-Deaza-2'-deoxyxanthosine (1a) and 7-deaza-2'-deoxyspongosine (2), two new pyrrolopyrimidine deoxynucleosides, have been prepared by nucleophilic displacement of the chloro substituents of the intermediate 2,4-dichloro-7-2-deoxy-3,5-di-O-(p-toluo