917353-86-7

Basic information

• Product Name: 4'-Ethyl-biphenyl-4-carboxylic acid methyl-{(S)-1-[(R)-3-(2,2,2-trifluoro-acetylamino)-pyrrolidine-1-carbonyl]-pyrrolidin-3-yl}-amide
• Synonyms: 4'-Ethyl-biphenyl-4-carboxylic acid methyl-{(S)-1-[(R)-3-(2,2,2-trifluoro-acetylamino)-pyrrolidine-1-carbonyl]-pyrrolidin-3-yl}-amide
• CAS NO: 917353-86-7
• Molecular Weight: 516.563
• Mol File: 917353-86-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 4'-Ethyl-biphenyl-4-carboxylic acid methyl-{(S)-1-[(R)-3-(2,2,2-trifluoro-acetylamino)-pyrrolidine-1-carbonyl]-pyrrolidin-3-yl}-amide(CAS DataBase Reference)
• NIST Chemistry Reference: 4'-Ethyl-biphenyl-4-carboxylic acid methyl-{(S)-1-[(R)-3-(2,2,2-trifluoro-acetylamino)-pyrrolidine-1-carbonyl]-pyrrolidin-3-yl}-amide(917353-86-7)
• EPA Substance Registry System: 4'-Ethyl-biphenyl-4-carboxylic acid methyl-{(S)-1-[(R)-3-(2,2,2-trifluoro-acetylamino)-pyrrolidine-1-carbonyl]-pyrrolidin-3-yl}-amide(917353-86-7)

Safety Data

• Hazardous Substances Data: 917353-86-7(Hazardous Substances Data)

Upstream product

• 764722-66-9 2,2,2-Trifluoro-N-[(R)-1-((S)-3-methylamino-pyrrolidine-1-carbonyl)-pyrrolidin-3-yl]-acetamide 
• 5731-13-5 4-(4-ethylphenyl)benzoic acid 
• 499774-45-7 2,2,2-trifluoro-N-pyrrolidin-3-yl-acetamide 
• 169750-00-9 (S)-1-benzyl-3-[[N-(t-butoxycarbonyl)]-N-methylamino]pyrrolidine 
• 400045-36-5 N-(1-benzyl-pyrrolidin-3-yl)-2,2,2-trifluoro-acetamide 
• 169749-99-9 (3S)-(-)-1-benzyl-3-(methylamino)pyrrolidine 
• 169750-01-0 (S)-3-[N-(tert-butoxycarbonyl)-N-methylamino]pyrrolidine 
• 764722-65-8 Methyl-{(S)-1-[(R)-3-(2,2,2-trifluoro-acetylamino)-pyrrolidine-1-carbonyl]-pyrrolidin-3-yl}-carbamic acid tert-butyl ester 
• 764722-45-4 3-(tert-butoxycarbonyl-methyl-amino)-pyrrolidine-1-carboxylic acid 4-nitro-phenyl ester 

Relevant articles and documents

Synthesis and structure-activity relationships of retro bis-aminopyrrolidine urea (rAPU) derived small-molecule antagonists of the melanin-concentrating hormone receptor-1 (MCH-R1). Part 2

The design, synthesis, and SAR of a series of retro bis-aminopyrrolidine ureas are described. Compounds from this series exhibited considerable binding affinity (Ki = 1 nM) and functional activity at MCH-R1, acceptable CYP2D6 inhibition, and good rat brain exposure.