917484-74-3

Basic information

• Product Name: (1R,2R)-N-acetyl-1,2-bis(trifluoromethanesulfonamido) cyclohexane
• Synonyms: (1R,2R)-N-acetyl-1,2-bis(trifluoromethanesulfonamido) cyclohexane
• CAS NO: 917484-74-3
• Molecular Weight: 420.354
• Mol File: 917484-74-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (1R,2R)-N-acetyl-1,2-bis(trifluoromethanesulfonamido) cyclohexane(CAS DataBase Reference)
• NIST Chemistry Reference: (1R,2R)-N-acetyl-1,2-bis(trifluoromethanesulfonamido) cyclohexane(917484-74-3)
• EPA Substance Registry System: (1R,2R)-N-acetyl-1,2-bis(trifluoromethanesulfonamido) cyclohexane(917484-74-3)

Safety Data

• Hazardous Substances Data: 917484-74-3(Hazardous Substances Data)

Upstream product

• 122833-60-7 N,N’-(1R,2R)-cyclohexane-1,2-diylbis(1,1,1-trifluoromethanesulfonamide) 
• 75-36-5 acetyl chloride 

Downstream Products

• 36283-44-0 N-acetyl-1-phenylethylamine 
• 3618-96-0 (S)-N-acetylphenylalanine 
• 1415568-38-5 C₁₂H₁₂⁽²⁾H₃NO₃ 
• 1415568-39-6 C₉H₁₀⁽²⁾H₃N₃O₃ 
• 36097-48-0 N^α-acetyl-L-histidine methyl ester 
• 118477-18-2 N-acetyl-cyclolysine 
• 1415568-34-1 C₁₄H₁₉NO₂ 
• 1415568-43-2 C₁₄H₁₆⁽²⁾H₃NO₂ 
• 550371-67-0 tert-butyl (3R)-3-acetamidopyrrolidine-1-carboxylate 
• 1415568-36-3 C₁₁H₁₇⁽²⁾H₃N₂O₃ 
• 1415568-29-4 C₁₀H₁₆⁽²⁾H₃NO 
• 100992-58-3 (S)-N-(1-cyclohexylethyl)acetamide 
• 1415568-35-2 C₁₇H₂₉NO₂Si 
• 1415568-44-3 C₁₇H₂₆⁽²⁾H₃NO₂Si 

Relevant articles and documents

Nanomole-scale assignment of configuration for primary amines using a kinetic resolution strategy

The absolute configurations of primary amines were assigned using a kinetic resolution strategy with Mioskowski's enantioselective 1-(R,R) and 2-(S,S) acylating agents. A simple mnemonic was developed to determine the configuration. A pseudoenantiomeric pair of reagents, 1-(R,R) and 2-(S,S)-d 3, was prepared and used to assay primary amines on a micromolar scale. The ESI-MS readout of the resulting acetamide products reproduced the selectivity factors from kinetic experiments. The method can be used on mixtures of amines and was validated with amine samples as small as 50 nmol.