917484-75-4Relevant articles and documents
Catalytic and stoichiometric approaches to the desymmetrisation of centrosymmetric piperazines by enantioselective acylation: A total synthesis of Dragmacidin A
Anstiss, Mark,Nelson, Adam
, p. 4135 - 4143 (2006)
The enantioselective desymmetrisation of centrosymmetric piperazines was investigated using both catalytic and stoichiometric asymmetric acylation approaches. The catalytic approach involved the desymmetrisation of 2,5-trans-dimethylpiperazine under the c