917805-85-7 Usage
Description
(+)-7-[4-(4-fluorophenyl)-6-isopropyl-2-(N-methyl-N-methylsulfonylamino)pyrimidin-5-yl]-(3R,5S)-dihydroxy-(E)-heptenoic acid tert-octylammonium salt is a complex organic compound featuring a pyrimidine ring attached to a dihydroxy heptenoic acid moiety, with additional fluorophenyl and isopropyl groups. (+)-7-[4-(4-fluorophenyl)-6-isopropyl-2-(N-methyl-N-methylsulfonylamino)pyrimidin-5-yl]-(3R,5S)-dihydroxy-(E)-heptenoic acid tert-octylammonium salt also contains a tert-octylammonium salt group and exhibits a specific (3R,5S) stereochemistry. Its intricate structure suggests potential biological activity, making it a candidate for pharmaceutical or research applications.
Uses
Used in Pharmaceutical Industry:
(+)-7-[4-(4-fluorophenyl)-6-isopropyl-2-(N-methyl-N-methylsulfonylamino)pyrimidin-5-yl]-(3R,5S)-dihydroxy-(E)-heptenoic acid tert-octylammonium salt is used as a potential pharmaceutical agent for its possible biological activity. (+)-7-[4-(4-fluorophenyl)-6-isopropyl-2-(N-methyl-N-methylsulfonylamino)pyrimidin-5-yl]-(3R,5S)-dihydroxy-(E)-heptenoic acid tert-octylammonium salt's complex structure and specific stereochemistry may contribute to its efficacy in targeting certain biological pathways or receptors, offering new avenues for the treatment of various diseases.
Used in Research Applications:
In the research field, (+)-7-[4-(4-fluorophenyl)-6-isopropyl-2-(N-methyl-N-methylsulfonylamino)pyrimidin-5-yl]-(3R,5S)-dihydroxy-(E)-heptenoic acid tert-octylammonium salt serves as a valuable compound for studying its interactions with biological systems. Its unique structure allows scientists to investigate its binding properties, mechanism of action, and potential applications in drug discovery and development processes.
Check Digit Verification of cas no
The CAS Registry Mumber 917805-85-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 9,1,7,8,0 and 5 respectively; the second part has 2 digits, 8 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 917805-85:
(8*9)+(7*1)+(6*7)+(5*8)+(4*0)+(3*5)+(2*8)+(1*5)=197
197 % 10 = 7
So 917805-85-7 is a valid CAS Registry Number.
917805-85-7Relevant articles and documents
PROCESS FOR PREPARING PURE AMORPHOUS ROSUVASTATIN CALCIUM
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Page/Page column 16-17, (2008/06/13)
A new process for preparing pure amorphous rosuvastatin calcium, substantially free of impurities, is disclosed. A process comprising hydrolysing a C1 to C5 alkyl ester of rosuvastatin, preferably methyl rosuvastatin or tert-butyl rosuvastatin, with a base, e.g. sodium hydroxide, in the presence of an aprotic solvent, preferably tetrahydrofuran and N,N-dimethyl acetamide, or in the presence of a mixture of an aprotic solvent and water, to obtain a solution of rosuvastatin salt, which may be converted to another rosuvastatin salt using another cation, e.g. with calcium cation to obtain rosuvastatin calcium. Rosuvastatin amine salts may be obtained as well. In another preferred aspect of the invention rosuvastatin free acid may be converted to various rosuvastatin salts, e.g. to rosuvastain calcium, rosuvastatin sodium or various rosuvastatin amine salts, including rosuvastatin solvates, e.g. rosuvastatin calcium hydrate. Rosuvastatin calcium is useful in the treatment of hyperlipidemia, hypercholesterolemia and atherosclerosis.
