917835-22-4Relevant articles and documents
Selectivity of N-versus O-alkylation in Mitsunobu reactions with various quinolinols and isoquinolinols
Hartung, Ryan E.,Wall, Mark C.,Lebreton, Sylvain,Smrcina, Martin,Patek, Marcel
, p. 1305 - 1313 (2017)
Reacting quinolinols and isoquinolinols under Mitsunobu conditions can give rise to N-alkylated products in addition to the normally desired O-alkylated structures. An in-depth study of how the solvent, reagent equivalents, position of the quinoline/isoqu