917918-80-0

Basic information

• Product Name: 7-Hydroxy-4-methoxy-6-azaindole
• Synonyms: 1,6-Dihydro-4-methoxy-7H-pyrrolo[2,3-c]pyridin-7-on;7-Hydroxy-4-methoxy-6-azaindole;1,6-Dihydro-4-methoxy-7H-pyrrolo[2,3-c]pyridin-7-one;7H-Pyrrolo[2,3-c]pyridin-7-one, 1,6-dihydro-4-Methoxy-;4-Methoxy-1H-pyrrolo[2,3-c]pyridin-7(6H)-one;7-Hydroxy-4-methoxy-6-azaindole-7
• CAS NO: 917918-80-0
• Molecular Formula: C₈H₈N₂O₂
• Molecular Weight: 164.17
• Product Categories: Aromatics Compounds;Aromatics;Heterocycles
• Mol File: 917918-80-0.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 519.4°C at 760 mmHg
• Flash Point: 267.9°C
• Appearance: /
• Density: 1.36g/cm³
• Vapor Pressure: 6.84E-11mmHg at 25°C
• Refractive Index: 1.619
• Storage Temp.: Refrigerator
• CAS DataBase Reference: 7-Hydroxy-4-methoxy-6-azaindole(CAS DataBase Reference)
• NIST Chemistry Reference: 7-Hydroxy-4-methoxy-6-azaindole(917918-80-0)
• EPA Substance Registry System: 7-Hydroxy-4-methoxy-6-azaindole(917918-80-0)

Safety Data

• Hazardous Substances Data: 917918-80-0(Hazardous Substances Data)

Usage

Uses

7-Hydroxy-4-methoxy-6-azaindole (cas# 917918-80-0) is a compound useful in organic synthesis.

InChI:InChI=1/C8H8N2O2/c1-12-6-4-10-8(11)7-5(6)2-3-9-7/h2-4,9H,1H3,(H,10,11)

Upstream product

• 67443-38-3 5-bromo-2-chloro-3-nitropyridine 

Downstream Products

• 619331-35-0 7-bromo-4-methoxy-6-azaindole 
• 446284-32-8 7-chloro-4-methoxy-1H-pyrrolo[2,3-c]pyridine 

Relevant articles and documents

Discovery and optimization of novel small-molecule HIV-1 entry inhibitors using field-based virtual screening and bioisosteric replacement

With the emergence of drug-resistant strains and the cumulative toxicities associated with current therapies, demand remains for new inhibitors of HIV-1 replication. The inhibition of HIV-1 entry is an attractive, yet underexploited therapeutic approach with implications for salvage and preexposure prophylactic regimens, as well as topical microbicides. Using the combination of a field-derived bioactive conformation template to perform virtual screening and iterative bioisosteric replacements, coupled with in silico predictions of absorption, distribution, metabolism, and excretion, we have identified new leads for HIV-1 entry inhibitors.