917956-88-8Relevant articles and documents
Synthesis of enantiopure 3,6,7,8-tetrahydrochromeno[7,8-d]imidazoles via asymmetric ketone hydrogenation in the presence of RuCl2[Xyl-P-Phos][DAIPEN]
Palmer, Andreas Marc,Chiesa, Vittoria,Holst, Hans Christof,Le Paih, Jacques,Zanotti-Gerosa, Antonio,Nettekoven, Ulrike
, p. 2102 - 2110 (2008/12/22)
The asymmetric hydrogenation of complex heterocyclic ketones 1 in the presence of the novel catalyst RuCl2[(S)-Xyl-P-Phos][(S)-DAIPEN] and a base afforded the corresponding alcohols 2 in good enantiomeric purity. The outcome of the reaction dep
INTERMEDIATES AND PROCESS FOR THE PRODUCTION OF 5-SUBSTITUTED TRICYCLIC BENZIMIDAZOLES
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Page/Page column 61-62, (2008/12/06)
The invention relates to compoun ds of the formula 1-a and 1-b, in which R1, R2, R3, Ar and PG have the meanings as indicated in the description. These compounds are valuable intermediates for the preparation of pharmaceutically active compounds.