91813-42-2 Usage
Description
2-Methyloxazolo[5,4-b]pyridine, also known as MOP or 2-MOP, is a heterocyclic chemical compound with a molecular formula C7H6N2O. It features an oxazole ring fused with a pyridine ring, classifying it within the oxazolopyridines. 2-Methyloxazolo[5,4-b]pyridine is significant in the pharmaceutical industry for its role as a building block in the synthesis of various bioactive compounds, such as drugs and agrochemicals. Moreover, 2-MOP has demonstrated potential as an antagonist of the nicotine acetylcholine receptor, suggesting its utility in nicotine addiction treatment or as a research tool for studying nicotine's biological effects. Its synthesis and properties are actively researched in organic chemistry, with applications extending to neurobiology and pharmacology studies.
Uses
Used in Pharmaceutical Industry:
2-Methyloxazolo[5,4-b]pyridine serves as a crucial building block for the synthesis of a wide array of bioactive compounds. Its unique structure contributes to the development of new drugs and agrochemicals, enhancing the industry's capacity to create effective and targeted treatments.
Used in Nicotine Addiction Treatment:
As an antagonist of the nicotine acetylcholine receptor, 2-MOP holds promise in the treatment of nicotine addiction. It may help reduce the rewarding effects of nicotine, thereby assisting individuals in overcoming their addiction to tobacco products.
Used in Neurobiology and Pharmacology Research:
2-Methyloxazolo[5,4-b]pyridine is utilized as a research tool in neurobiology and pharmacology. Its ability to interact with nicotine receptors makes it a valuable asset in studying the biological effects of nicotine and related compounds, furthering our understanding of addiction mechanisms and potential therapeutic interventions.
Check Digit Verification of cas no
The CAS Registry Mumber 91813-42-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 9,1,8,1 and 3 respectively; the second part has 2 digits, 4 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 91813-42:
(7*9)+(6*1)+(5*8)+(4*1)+(3*3)+(2*4)+(1*2)=132
132 % 10 = 2
So 91813-42-2 is a valid CAS Registry Number.
InChI:InChI=1/C7H6N2O/c1-5-9-6-3-2-4-8-7(6)10-5/h2-4H,1H3
91813-42-2Relevant articles and documents
Flash Photolysis Study of 3-Methylisoxazolopyridine
Donati, Donato,Ponticelli, Fabio,Bicchi, Paola,Meucci, Mario
, p. 5271 - 5274 (2007/10/02)
The photoreactivity of the title compound has been examined in MeOH, PriOH, MeCN, and MeCN/as-dimethylhydrazine solutions.A ketenimine and a spiroazirine intermediate account for the final products as well as for the transients observed in the flash photolysis experiments.It is also found that acid catalysis plays an important role in the reaction of spiroazirine to oxazolopyridine.
2-ARYL-OXAZOLO- AND THIAZOLOPYRIDINES. SYNTHESIS VIA CYCLIZATION OF N-(2-CHLORO-3-PYRIDINYL)ARYLAMIDES AND THIOAMIDES
Couture, Axel,Grandclaudon, Pierre
, p. 1383 - 1385 (2007/10/02)
Chloropyridinylenamides can by easily converted into oxazolo- and thiazolo pyridines by treatment with polyphosphoric acid and Lawesson reagent respectively.
