91890-89-0

Basic information

• Product Name: 3-Penten-1-one, 2-hydroxy-1-phenyl-
• CAS NO: 91890-89-0
• Molecular Formula: C11H12O2
• Molecular Weight: 176.215
• Mol File: 91890-89-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 3-Penten-1-one, 2-hydroxy-1-phenyl-(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Penten-1-one, 2-hydroxy-1-phenyl-(91890-89-0)
• EPA Substance Registry System: 3-Penten-1-one, 2-hydroxy-1-phenyl-(91890-89-0)

Safety Data

• Hazardous Substances Data: 91890-89-0(Hazardous Substances Data)

Upstream product

• 100-52-7 benzaldehyde 
• 123-73-9 crotonaldehyde 
• 21663-35-4 1-phenyl-pent-3-ene-1,2-diol 
• 54123-83-0 (E)-1-Hydroxy-1-phenyl-pent-3-en-2-one 

Relevant articles and documents

α,β-unsaturated aldehydes as substrates for asymmetric C-C bond forming reactions with thiamin diphosphate (ThDP)-dependent enzymes

The enzymes benzaldehyde lyase (BAL) from Pseudomonas fluorescens, benzoylformate decarboxylase (BFD) from Pseudomonas putida and pyruvate decarboxylase (PDC) from Saccharomyces cerevisiae provide different C-C bond forming possibilities of α,β-unsaturated aldehydes with aliphatic and aromatic aldehydes. Structure elucidation and determination of the absolute configuration of the products, which were obtained with high regio- and stereoselectivity were carried out. Selective 1,2-reactivity with yields of 75% and >98% ee, for one single isomer (A) were obtained, by choosing the suitable enzyme in combination with the appropriate substrates. By varying enzymes or substrates the regioisomeric hydroxy ketones C, with up to >99% ee, can be obtained. The application of these new chiral building blocks in the synthesis of natural products or biological active substances is considerably facilitated by applying the different ThDP-dependent enzymes as catalysts.