919285-21-5

Basic information

• Product Name: (4-{2-[3-(2,6-dichloro-phenyl)-5-methyl-isoxazol-4-ylmethoxy]-ethoxy}-2-methyl-phenoxy)-acetic acid methyl ester
• Synonyms: (4-{2-[3-(2,6-dichloro-phenyl)-5-methyl-isoxazol-4-ylmethoxy]-ethoxy}-2-methyl-phenoxy)-acetic acid methyl ester
• CAS NO: 919285-21-5
• Molecular Weight: 480.345
• Mol File: 919285-21-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (4-{2-[3-(2,6-dichloro-phenyl)-5-methyl-isoxazol-4-ylmethoxy]-ethoxy}-2-methyl-phenoxy)-acetic acid methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: (4-{2-[3-(2,6-dichloro-phenyl)-5-methyl-isoxazol-4-ylmethoxy]-ethoxy}-2-methyl-phenoxy)-acetic acid methyl ester(919285-21-5)
• EPA Substance Registry System: (4-{2-[3-(2,6-dichloro-phenyl)-5-methyl-isoxazol-4-ylmethoxy]-ethoxy}-2-methyl-phenoxy)-acetic acid methyl ester(919285-21-5)

Safety Data

• Hazardous Substances Data: 919285-21-5(Hazardous Substances Data)

Upstream product

• 175204-38-3 [3-(2,6-dichlorophenyl)-5-methyl-4-isoxazolyl]methanol 
• 3919-76-4 3-(2,6-dichloro-phenyl)-5-methyl-isoxazole-4-carboxylic acid 
• 303225-22-1 4-(chloromethyl)-3-(2,6-dichlorophenyl)-5-methylisoxazole 
• 870194-46-0 2-[3-(2,6-dichloro-phenyl)-5-methyl-isoxazol-4-ylmethoxy]-ethanol 
• 317319-10-1 methyl (4-hydroxy-2-methylphenoxy)acetate 

Relevant articles and documents

3,4,5-Trisubstituted isoxazoles as novel PPARδ agonists: Part 1

We report the identification of a novel series of trisubstituted isoxazoles as PPAR activators from a high-throughput screen. A series of structural optimizations led to improved efficacy and excellent functional receptor selectivity for PPARδ. The isoxazoles represent a series of agonists which display a scaffold that lies outside the typical PPAR agonist motif.