92-39-7Relevant articles and documents
Antioxidant and method for preparing antioxidant
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Paragraph 0011; 0046; 0048; 0054; 0056; 0062; 0064, (2021/08/06)
The invention discloses an antioxidant and a method for preparing the antioxidant. An intermediate 2 reacts with an intermediate 5 to obtain an intermediate 14, the intermediate 14 isoxidized with potassium permanganate, an esterification reaction is then carried out with an intermediate 13 to obtain an intermediate 15, the intermediate 15 is reduced with tin powder to obtain an intermediate 16, the intermediate 16 and the intermediate 8 are subjected to dehydration condensation, the antioxidant is prepared, the antioxidant contains a large number of sulfur atoms, the sulfur atoms can be oxidized to form sulfoxide and sulfone compounds, the antioxidant has good oxidation resistance, free radicals generated by macromolecules can be captured, then the free radical branching reaction is inhibited, and the antioxidant activity is improved. The oxidation resistance of the high-molecular material is improved, and the self relative molecular mass is large and is not easy to separate out from the high-molecular material.
Efficient and regioselective synthesis of phenothiazine via ferric citrate catalyzed C-S/C-N cross-coupling
Das, Tonmoy Chitta,Quadri, Syed Aziz Imam,Farooqui, Mazahar
supporting information, p. 16 - 24 (2019/05/04)
Efficient C-S and C-N cross-coupling reactions have been developed for regioselective, scalable and environmentally benign synthesis of substituted phenothiazine derivatives. Cross-coupling reactions were demonstrated on various challenging substrates using non-toxic, highly economical, readily available ferric citrate as a catalyst to get desired product with high regioselectivity. Atom economy is the added advantage of this protocol since additional N-protection step before coupling and eventual deprotection of the same to obtain the desired product arenot required. To the best of our knowledge, this is the first report on the use of inexpensive ferric citrate as a catalyst without involving any ligand for the synthesis of regioselectively substituted phenothiazine.
Transition-metal-free synthesis of phenothiazines from S-2-acetamidophenyl ethanethioate and ortho-dihaloarenes
Zhou, Yue,Zeng, Qingle,Zhang, Li
supporting information, p. 710 - 715 (2017/03/27)
An efficient cesium carbonate-mediated synthesis of phenothiazine derivatives from S-2-acetamidophenyl ethanethioates and ortho-dihaloarenes has been developed. This protocol affords an efficient approach for the construction of phenothiazine derivatives without the need of transition-metal catalyst or ligand. A plausible mechanism is proposed.
