92-59-1 Usage
Description
N-Benzyl-N-ethylaniline is a colorless to light yellow oily liquid that is insoluble in water and denser than water, causing it to sink when in contact with water. It may cause irritation to the skin, eyes, and mucous membranes, and has the potential to be toxic through ingestion, inhalation, and skin absorption.
Uses
Used in the Manufacture of Dyes:
N-Benzyl-N-ethylaniline is used as a chemical intermediate in the production of dyes, contributing to the development of various colorants for different applications.
Used in Organic Syntheses:
N-Benzyl-N-ethylaniline serves as a valuable building block in organic synthesis, enabling the creation of a range of organic compounds for diverse uses.
Used in Scientific Research:
In a study, N-Benzyl-N-ethylaniline was utilized to investigate the electron transfer quenching dynamics of excited perylene and cyanoperylene in various donating solvents, providing insights into the behavior of these compounds in different environments.
Air & Water Reactions
Insoluble in water.
Reactivity Profile
N-Benzyl-N-ethylaniline neutralizes acids in exothermic reactions to form salts plus water. May be incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides. Flammable gaseous hydrogen may be generated in combination with strong reducing agents, such as hydrides.
Health Hazard
TOXIC; inhalation, ingestion or skin contact with material may cause severe injury or death. Contact with molten substance may cause severe burns to skin and eyes. Avoid any skin contact. Effects of contact or inhalation may be delayed. Fire may produce irritating, corrosive and/or toxic gases. Runoff from fire control or dilution water may be corrosive and/or toxic and cause pollution.
Fire Hazard
Combustible material: may burn but does not ignite readily. When heated, vapors may form explosive mixtures with air: indoors, outdoors and sewers explosion hazards. Contact with metals may evolve flammable hydrogen gas. Containers may explode when heated. Runoff may pollute waterways. Substance may be transported in a molten form.
Flammability and Explosibility
Notclassified
Purification Methods
Dry the amine over KOH pellets and fractionate it. The picrate crystallises from *C6H6 as lemon yellow crystals m 126-128o (softening at 120o). [Forrest et al. J Chem Soc 303 1951, IR: Hill & Meakins J Chem Soc 760 1958, Beilstein 12 H 1026, 12 IV 2176.]
Check Digit Verification of cas no
The CAS Registry Mumber 92-59-1 includes 5 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 2 digits, 9 and 2 respectively; the second part has 2 digits, 5 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 92-59:
(4*9)+(3*2)+(2*5)+(1*9)=61
61 % 10 = 1
So 92-59-1 is a valid CAS Registry Number.
InChI:InChI=1/C15H17N/c1-2-16(15-11-7-4-8-12-15)13-14-9-5-3-6-10-14/h3-12H,2,13H2,1H3
92-59-1Relevant articles and documents
NEW METHOD FOR THE SYNTHESIS OF UNSYMMETRICAL TERTIARY AMINES
-
Paragraph 0092, (2020/08/25)
Disclosed is a new method for the synthesis of unsymmetrical tertiary amines using alcohol and an imine, and to new tertiary amines.
Transition-Metal-Free Three-Component Synthesis of Tertiary Aryl Amines from Nitro Compounds, Boronic Acids, and Trialkyl Phosphites
Roscales, Silvia,Csáky, Aurelio G.
, p. 111 - 117 (2019/11/16)
The synthesis of aromatic amines is of continuous interest in chemistry. An exceptionally versatile three-component reaction that directly transforms inexpensive nitro compounds, boronic acids, and trialkyl phosphites into tertiary aromatic amines has been realized. The reaction tolerates alkyl and aryl substituents on the nitro and boronic acid moieties, as well as functionalized phosphites. No transition-metal catalysis is required. The method is orthogonal to other classical metal-catalyzed syntheses since it tolerates the presence of halogens, and also permits the synthesis of functionalized compounds such as α-amino ester derivatives. (Figure presented.).
Method for efficiently realizing N-alkylation reaction by using cyclic iridium catalyst
-
Paragraph 0227-0233, (2020/11/10)
The invention discloses a method for efficiently realizing N-alkylation reaction by using a cyclic iridium catalyst, and belongs to the technical field of pharmaceutical and chemical synthesis. The preparation method comprises the following steps of: taking amines and alcohol compounds as raw materials, a cyclic iridium complex as a catalyst and water or an organic solvent as a reaction medium, heating, stirring and reacting for 12-24 hours under the protection of inert gas, cooling to room temperature after the reaction is finished, carrying out reduced pressure distillation and concentrationto obtain a crude product, and carrying out column chromatography purification to obtain a series of amine compounds. The synthesis method of the amine compound is simple to operate, easily availablein raw materials and low in price; the method is high in reaction efficiency, good in N-alkylation selectivity, good in adaptability to various functional groups, wide in substrate universality and environmentally friendly, is carried out at the gram level, shows the potential of industrially synthesizing the N-alkylamine compound, and has wide application prospects in the fields of medicines, organic synthesis and the like.
