92052-59-0

Basic information

• Product Name: 7-[(1R,2R,3R,5R)-3,5-Dihydroxy-2-((E)-(S)-3-hydroxy-oct-1-enyl)-cyclopentyl]-6-oxo-heptanoic acid methyl ester
• CAS NO: 92052-59-0
• Molecular Weight: 384.513
• Mol File: 92052-59-0.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 7-[(1R,2R,3R,5R)-3,5-Dihydroxy-2-((E)-(S)-3-hydroxy-oct-1-enyl)-cyclopentyl]-6-oxo-heptanoic acid methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 7-[(1R,2R,3R,5R)-3,5-Dihydroxy-2-((E)-(S)-3-hydroxy-oct-1-enyl)-cyclopentyl]-6-oxo-heptanoic acid methyl ester(92052-59-0)
• EPA Substance Registry System: 7-[(1R,2R,3R,5R)-3,5-Dihydroxy-2-((E)-(S)-3-hydroxy-oct-1-enyl)-cyclopentyl]-6-oxo-heptanoic acid methyl ester(92052-59-0)

Safety Data

• Hazardous Substances Data: 92052-59-0(Hazardous Substances Data)

Upstream product

• 77644-11-2 7-{(1R,2R,3R,5R)-3-(tert-Butyl-dimethyl-silanyloxy)-2-[(E)-(S)-3-(tert-butyl-dimethyl-silanyloxy)-oct-1-enyl]-5-hydroxy-cyclopentyl}-6-oxo-heptanoic acid methyl ester 
• 112329-43-8 7-Hydroxy-6-nitro-heptanoic acid methyl ester 
• 92052-44-3 7-{(1R,2R,3R,5S)-3-(tert-Butyl-dimethyl-silanyloxy)-2-[(E)-(S)-3-(tert-butyl-dimethyl-silanyloxy)-oct-1-enyl]-5-hydroxy-cyclopentyl}-6-nitro-heptanoic acid methyl ester 
• 13154-40-0 6-nitrohexanoic acid methyl ester 
• 92077-99-1 11,15-O-Bis(tert-butyldimethylsilyl)-6-nitro-PGE₁ methyl ester 
• 88462-11-7 Methyl 6-nitro-6-heptenoate 
• 14273-90-6 methyl 6-bromohexanoate 

Relevant articles and documents

Nitro-Olefin Trapping Reactions of Enolates In Situ Generated by Conjugate Addition Reaction: Short Syntheses of PGE1, 6-Oxo-PGE1, 6-Oxo-PGF1α, and PGI2

The nitro-olefin trapping of the enolates in situ generated by conjugate addition of organocopper reagents to the chiral oxygenated cyclopentenone synthon, R-4, gives the three-component coupling products in a regiospecific manner.The intermediary nitronate anion 17 is further transformed into the nitro compound or 6-oxo-PGE1 (19) in a single pot.This coupling reaction is applicable to syntheses of naturally occurring prostaglandins such as PGE1, 6-oxo-PGF1α, and PGI2.