921-08-4

Basic information

• Product Name: 2-chloro-3-methylbutanoic acid
• Synonyms: 2-Chloro-3-methylbutanoic acid; butanoic acid, 2-chloro-3-methyl-
• CAS NO: 921-08-4
• Molecular Formula: C₅H₉ClO₂
• Molecular Weight: 136.5768
• Mol File: 921-08-4.mol
• Article Data: 30

Chemical Properties

• Boiling Point: 210.3°C at 760 mmHg
• Flash Point: 81°C
• Density: 1.159g/cm³
• Vapor Pressure: 0.0768mmHg at 25°C
• Refractive Index: 1.447
• CAS DataBase Reference: 2-chloro-3-methylbutanoic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 2-chloro-3-methylbutanoic acid(921-08-4)
• EPA Substance Registry System: 2-chloro-3-methylbutanoic acid(921-08-4)

Safety Data

• Hazardous Substances Data: 921-08-4(Hazardous Substances Data)

Usage

General Description

2-chloro-3-methylbutanoic acid is a chemical compound with the molecular formula C5H9ClO2. It is a carboxylic acid derivative that consists of a butanoic acid with a chloro and a methyl substituent at the 2 and 3 positions, respectively. 2-chloro-3-methylbutanoic acid is used as a reactant in organic synthesis and is known for its strong odor. It is also used in the production of pharmaceuticals and agrochemicals. Additionally, it is considered to be a hazardous substance and proper safety precautions should be taken when handling it.

Upstream product

• 503-74-2 3-methylbutyric acid 
• 89211-85-8 2-chloro-3-methyl-1-nitro-butane 
• 601-79-6 isopropylmalonic acid 
• 70477-21-3 2-chloro-3-methylbutanenitrile 
• 539-66-2 sodium isovalerate 
• 516-06-3 D,L-valine 
• 54235-91-5 Chloro(isopropyl)malonsaeure 
• 72-18-4 L-valine 
• 75-26-3 isopropyl bromide 
• 7782-50-5 chlorine 
• 7732-18-5 water 
• 55068-34-3 2-chloro-3-methyl-butan-1-ol 
• 7697-37-2 nitric acid 
• 32766-45-3 1,1,1-trichloro-3-methylbutan-2-ol 

Downstream Products

• 4026-18-0 2-hydroxy-3-methylbutanoic acid 
• 516-06-3 D,L-valine 
• 59011-96-0 3-Methyl-2-[4-(4-trifluoromethyl-phenoxy)-phenoxy]-butyric acid 
• 21671-21-6 (S)-3-methyl-2-(phenylamino)butanoic acid 
• 83119-44-2 α-(2,3-dichloro-4-methoxyphenylthio)isovaleric acid 
• 129585-68-8 2-<(4,5-diphenylimidazol-2-yl)thio>-3-methylbutanoic acid 
• 82378-47-0 (R)-2-isopropyloxirane 
• 114351-37-0 2-Chloro-3-methyl-N-{2-[2-(pyridin-2-ylcarbamoyl)-acetyl]-6-trifluoromethyl-phenyl}-butyramide 
• 114377-09-2 2-[(2-chloro-1-oxo-3-methylbutyl)-amino]-β-oxo-N-(2-thiazolyl)-(3-trifluoromethyl)-benzene-propanamide 
• 143238-72-6 2'-<6'-((2''S-2''-chloro-3''-methylbutanoyl)oxy)>naphthyl 4-decyloxybenzoate 
• 137349-26-9 (1-phthalimido-2-methyl)propyl-5-phenyloxazole 
• 100128-75-4 <2-Azido-isovaleryl>-<4-nitro-benzolsulfonsaeureimid> 
• 100255-59-2 <2-Azido-isovaleryl>-p-toluolsulfonsaeureimid 

Relevant articles and documents

CRYSTALLINE FORMS OF A CD73 INHIBITOR

The present invention relates to crystalline forms of 5-[5-[2-isopropylcyclopropyl] -6-methyl-pyridazin-3-yl]-1H-pyrimidine-2,4-dione, and pharmaceutical compositions comprising them, which inhibit the activity of CD73 and are useful for treating cancer.

CD73 INHIBITORS

The present invention provides 5-[5]-[2-cycloa Ikyl ]-6-pyridazin-3-yl ]- IH-pyrimidine-2,4-dione compounds, or pharmaceutically acceptable salts thereof, that inhibit the activity of CD73 and are useful in treating cancer. (Formula (I))

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