921-14-2

Basic information

• Product Name: N,N-DIISOPROPYLHYDRAZINE
• Synonyms: N,N-DIISOPROPYLHYDRAZINE
• CAS NO: 921-14-2
• Molecular Formula: C₆H₁₆N₂
• Molecular Weight: 116.2
• Mol File: 921-14-2.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 153.9°Cat760mmHg
• Flash Point: 30.3°C
• Appearance: /
• Density: 0.834g/cm³
• Vapor Pressure: 3.27mmHg at 25°C
• Refractive Index: 1.444
• PKA: 8.05±0.70(Predicted)
• CAS DataBase Reference: N,N-DIISOPROPYLHYDRAZINE(CAS DataBase Reference)
• NIST Chemistry Reference: N,N-DIISOPROPYLHYDRAZINE(921-14-2)
• EPA Substance Registry System: N,N-DIISOPROPYLHYDRAZINE(921-14-2)

Safety Data

• Hazardous Substances Data: 921-14-2(Hazardous Substances Data)

Usage

InChI:InChI=1/C6H16N2/c1-5(2)8(7)6(3)4/h5-6H,7H2,1-4H3

Upstream product

• 108-18-9 diisopropylamine 
• 67-63-0 isopropyl alcohol 
• 75-26-3 isopropyl bromide 
• 601-77-4 N-nitrosodiisopropylamine 

Downstream Products

• 18481-95-3 1,1-diisopropyl-4-phenyl thiosemicarbazide 
• 60678-72-0 N-Isopropyl-N'-methyl-hydrazin 
• 29280-89-5 Thioacetyl-N,N-diisopropyl-hydrazin 
• 59856-63-2 3-Methyl-1-ethyl-5,5-diisopropyl-3,4-dihydroformazan 
• 63857-13-6 2-(Diisopropyl-hydrazonomethyl)-3-phenyl-propionic acid methyl ester 
• 65112-04-1 1β-oxo-6β-(2-phenyl-acetylamino)-1λ⁴-penicillanic acid N',N'-diisopropyl-hydrazide 
• 38706-70-6 C₁₄H₂₃N₃ 
• 13304-31-9 Tetra-isopropyl-2-tetrazen 
• 13304-31-9 1,1,4,4-Tetraisopropyl-2-tetrazen 
• 29280-88-4 N,N-Diisopropyl-N'-pivaloyl-hydrazin 
• 58647-43-1 4-Benzyl-1,1-diisopropyl-thiosemicarbazid 
• 5098-81-7 N,N-Diisopropyl-N'-(2,6-dichlorbenzyliden)-hydrazin 
• 65112-17-6 N-Benzoyl-N'N'-diisopropylhydrazin 
• 64113-41-3 N,N-Dimethyl-N',N'-diisopropyl-2-tetrazen 

Relevant articles and documents

Synthesis of multi-substituted 1,2,4-triazoles utilising the ambiphilic reactivity of hydrazones

The synthesis of N-alkyl-1H-1,2,4-triazoles from N,N-dialkylhydrazones and nitriles via formal [3+2] cycloaddition including the C-chlorination/nucleophilic addition/cyclisation/dealkylation sequence was developed. This sequential reaction utilising the in situ generation of hydrazonoyl chloride based on the ambiphilic reactivity of hydrazones afforded a variety of multi-substituted N-alkyl-triazoles in high yields. The synthetic utility of multi-substituted triazoles was also demonstrated by further transformations.

Reduction of Nitrosamines with Aqueous Titanium Trichloride: Convenient Preparation of Aliphatic Hydrazines

The reduction of selected nitrosamines by aqueous TiCl3 has been investigated.In general, aliphatic nitrosamines were converted in good yield to the corresponding hydrazines, with little overreduction to the amines.Reaction proceeded rapidly at room temperature in both alkaline and acidic media.A variety of N,N-dialkylhydrazines have been isolated by using the TiCl3 method, which compares favorably with previously reported procedures for preparatively converting nitrosamines to hydrazines.In the reduction of N-nitroso-N-methylaniline, the proportion of amine in the product increased significantly as the pH of the reaction mixture was lowered, presumably reflecting the known instability of arylalkylnitrosamines in strong acid, coupled with a ready reducibility of the corresponding Fischer-Hepp intermediates; some tendency toward reductive cleavage of the N-aryl-N-alkylhydrazine's N-N-bond was also noted.Reduction of an α-nitrosamino ether gave the monoalkylhydrazine as the major product, while all other reducing agents studied converted this starting material chiefly to a mixture of primary and secondary amines.