92118-22-4 Usage
Chemical Properties
Oil
Uses
Different sources of media describe the Uses of 92118-22-4 differently. You can refer to the following data:
1. A nicotine analogue
2. A novel Nicotine (N412420) analogue, a neuronal nicotinic receptor.
Check Digit Verification of cas no
The CAS Registry Mumber 92118-22-4 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 9,2,1,1 and 8 respectively; the second part has 2 digits, 2 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 92118-22:
(7*9)+(6*2)+(5*1)+(4*1)+(3*8)+(2*2)+(1*2)=114
114 % 10 = 4
So 92118-22-4 is a valid CAS Registry Number.
InChI:InChI=1/C10H14N2/c1-12-6-4-10(8-12)9-3-2-5-11-7-9/h2-3,5,7,10H,4,6,8H2,1H3
92118-22-4Relevant articles and documents
Regioselective synthesis of 3-aryl substituted pyrrolidines via palladium catalyzed arylation: Pharmacological evaluation for central dopaminergic and serotonergic activity
Sonesson, Clas,Wikstroem, Hakan,Smith, Martin W.,Svensson, Kjell,Carlsson, Arvid,Waters, Nicholas
, p. 241 - 246 (2007/10/03)
A series of 3-arylpyrrolidines has been synthesised via palladium catalyzed arylation and evaluated for dopaminergic and serotonergic activity in vitro and in vivo. Compounds substituted by electron withdrawing groups on the meta position of the aromatic ring, were found to be preferential dopamine autoreceptor antagonists.