921195-79-1Relevant articles and documents
APOPTOSIS-INDUCING AGENTS FOR THE TREATMENT OF CANCER AND IMMUNE AND AUTOIMMUNE DISEASES
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Page/Page column 43, (2010/08/07)
Disclosed are compounds which inhibit the activity of anti-apoptotic Bcl-2 proteins, compositions containing the compounds and methods of treating diseases during which is expressed anti-apoptotic Bcl-2 protein.
Design, synthesis, and computational studies of inhibitors of Bcl-X L
Park, Cheol-Min,Oie, Tetsuro,Petros, Andrew M.,Zhang, Haichao,Nimmer, Paul M.,Henry, Rodger F.,Elmore, Steven W.
, p. 16206 - 16212 (2007/10/03)
One of the primary objectives in the design of protein inhibitors is to shape the three-dimensional structures of small molecules to be complementary to the binding site of a target protein. In the course of our efforts to discover potent inhibitors of Bc