921760-46-5 Usage
Description
6-Bromospiro[chroman-2,4'-piperidin]-4-one hydrochloride is a chemical compound that features a spiro-linked chroman and piperidine structure. It is characterized by the presence of a bromo substituent and a hydrochloride group, which contribute to its unique chemical properties and potential applications in various fields.
Uses
Used in Pharmaceutical Industry:
6-Bromospiro[chroman-2,4'-piperidin]-4-one hydrochloride is used as an acetyl coenzyme A carboxylase (ACC) inhibitor for the development of pharmaceutical agents. ACC is a key enzyme involved in the regulation of fatty acid synthesis and energy metabolism. Inhibition of this enzyme can lead to the reduction of fatty acid synthesis, making it a potential target for the treatment of metabolic disorders and obesity.
In the synthesis of ACC inhibitors, 6-Bromospiro[chroman-2,4'-piperidin]-4-one hydrochloride serves as a valuable intermediate or building block. Its unique structure allows for the creation of novel compounds with improved potency, selectivity, and pharmacokinetic properties. By incorporating this compound into the design of new drugs, researchers can explore its potential in addressing unmet medical needs and developing more effective therapeutic options for patients.
Check Digit Verification of cas no
The CAS Registry Mumber 921760-46-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 9,2,1,7,6 and 0 respectively; the second part has 2 digits, 4 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 921760-46:
(8*9)+(7*2)+(6*1)+(5*7)+(4*6)+(3*0)+(2*4)+(1*6)=165
165 % 10 = 5
So 921760-46-5 is a valid CAS Registry Number.
921760-46-5Relevant articles and documents
MODULATORS OF INDOLEAMINE 2,3-DIOXYGENASE
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, (2019/01/17)
Provided are IDO inhibitor compounds of Formula I and pharmaceutically acceptable salts thereof, their pharmaceutical compositions, their methods of preparation, and methods for their use in the prevention and/or treatment of diseases. Formula (I):
Substituted spirochromanone derivatives
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Page/Page column 42, (2008/12/06)
The invention relates to a compound of a general formula (I): wherein Ar1 represents a group formed from an aromatic ring selected from a group consisting of indole, 1H-indazole, 2H-indazole, 1H-thieno[2,3-c]pyrazole, 1H-pyrazolo[3,4-b]pyridine
N-SULFAMOYL-N’-BENZOPYRANPIPERIDINES AS INHBITORS OF CARBONIC ANHYDRASES
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Page/Page column 31-32, (2008/06/13)
The present invention relates to novel N-sulfamoyl-N'-benzopyranpiperidines of general formula (I) and their physiologically acceptable acid addition salts, to pharmaceutical compositions comprising them, processes for their preparation, and their use for the prophylaxis and/or treatment and/or prevention and/or inhibition of glaucoma, epilepsy, bipolar disorders, migraine, neuropathic pain, obesity, type II diabetes, metabolic syndrome, alcohol dependence, and/or cancer, and its concomitant and/or secondary diseases or conditions.
