92199-07-0

Basic information

• Product Name: 1H-Indole, 2,3-dihydro-7-phenyl-
• Synonyms: 7-Phenyl-2,3-dihydro-indol
• CAS NO: 92199-07-0
• Molecular Formula: C14H13N
• Molecular Weight: 195.264
• Mol File: 92199-07-0.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 369.6±32.0 °C(Predicted)
• Density: 1.085±0.06 g/cm3(Predicted)
• CAS DataBase Reference: 1H-Indole, 2,3-dihydro-7-phenyl-(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-Indole, 2,3-dihydro-7-phenyl-(92199-07-0)
• EPA Substance Registry System: 1H-Indole, 2,3-dihydro-7-phenyl-(92199-07-0)

Safety Data

• Hazardous Substances Data: 92199-07-0(Hazardous Substances Data)

Usage

Chemical class

Indole class of organic compounds

Structure

Bicyclic structure consisting of a six-membered benzene ring fused to a five-membered nitrogen-containing pyrrole ring

Usage

Building block in the synthesis of pharmaceuticals, agrochemicals, and organic compounds

Biological activities

Antiviral, anticancer, and anti-inflammatory properties

Aromatic properties

Used in the production of dyes, fragrances, and flavors

Upstream product

• 1863-21-4 7-(phenyl)-1H-indole 
• 7633-56-9 N-aminoindoline 
• 71-43-2 benzene 

Downstream Products

• 1254363-77-3 1-((4-methoxyphenyl)sulfonyl)-7-phenylindoline 
• 1863-21-4 7-(phenyl)-1H-indole 

Relevant articles and documents

Pyridazine N-Oxides as Precursors of Metallocarbenes: Rhodium-Catalyzed Transannulation with Pyrroles

Pyridazine N-oxides are used for the first time as precursors of metallocarbenes. These nitrogen-rich heterocycles led to the discovery of a novel acceptor and donor-acceptor enalcarbenoids. The synthetic utility of these metallocarbenes was demonstrated in the rhodium-catalyzed denitrogenative transannulation of pyridazine N-oxides with pyrroles to the valuable alkyl, 7-aryl, and 7-styryl indoles. The transannulation strategy was applied to the synthesis of a potent anticancer agent.

A TRIFLUOROMETHANESULFONIC ACID-CATALYZED REACTION OF ARYLHYDRAZINES WITH BENZENE

Arylhydrazines reacted with benzene in the presence of trifluoromethanesulfonic acid (TFSA) to give aminobiphenyls.This is a general method for the synthesis of aminobiphenyls.