92251-17-7

Basic information

• Product Name: 2-Cyclohexen-1-one, 3-ethoxy-5-phenyl-
• CAS NO: 92251-17-7
• Molecular Formula: C14H16O2
• Molecular Weight: 216.28
• Mol File: 92251-17-7.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 2-Cyclohexen-1-one, 3-ethoxy-5-phenyl-(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Cyclohexen-1-one, 3-ethoxy-5-phenyl-(92251-17-7)
• EPA Substance Registry System: 2-Cyclohexen-1-one, 3-ethoxy-5-phenyl-(92251-17-7)

Safety Data

• Hazardous Substances Data: 92251-17-7(Hazardous Substances Data)

Upstream product

• 493-72-1 5-phenyl-cyclohexane-1,3-dione 
• 64-67-5 diethyl sulfate 
• 64-17-5 ethanol 
• 7664-93-9 sulfuric acid 
• 75-03-6 ethyl iodide 
• 1896-62-4 (E)-benzalacetone 
• 100-52-7 benzaldehyde 

Downstream Products

• 35376-41-1 5-phenylcyclohex-2-en-1-one 
• 51367-64-7 3-chloro-5-phenylcyclohex-2-en-1-one 
• 857778-18-8 3-bromo-5-phenylcyclohex-2-en-1-one 
• 116704-21-3 trans (<3-D>5-phenyl 2-cyclohexenyl) benzoate 
• 116704-21-3 cis (<3-D>5-phenyl 2-cyclohexenyl) benzoate 
• 116704-23-5 trans (<3-D> 5-phenyl 2-cyclohexenyl) methyl sulfide 
• 116704-14-4 trans (<1-D> 5-phenyl 2-cyclohexenyl) methyl sulfide 
• 116704-20-2 cis <3-D> 5-phenyl 2-cyclohexenol 

Relevant articles and documents

Iodine-Promoted Semmler–Wolff Reactions: Step-Economic Access to meta-Substituted Primary Anilines via Aromatization

An atom- and step-economic access to an array of unprotected meta-substituted primary anilines was disclosed using the Semmler–Wolff reaction, promoted by molecular iodine. Therein, noble metal catalysts and inert atmosphere are unnecessary while the forcing reaction conditions and the lengthy synthesis can be avoided. The synthetic utility of this approach is evident in the de novo syntheses of three bioactive molecules with good total yields.

Catalytic Enantioselective Nitroso Diels-Alder Reaction

The nitroso Diels-Alder (NDA) reaction is an attractive strategy for the synthesis of 3,6-dihydro-1,2-oxazines and 1-amino-4-hydroxy-2-ene derivatives. Herein we report the Cu(I)-DTBM-Segphos catalyzed asymmetric intermolecular NDA reaction of variously substituted cyclic 1,3-dienes using highly reactive nitroso compounds derived from pyrimidine and pyridazine derivatives. In most of the cases studied, the cycloadducts were obtained in high yields (up to 99%) with very high regio-, diastereo-, and enantioselectivities (up to regioselectivity > 99:1, d.r. > 99:1, and >99% ee). As an application of this methodology, formal syntheses of conduramine A-1 and narciclasine were accomplished.