922527-86-4

Basic information

• Product Name: N-benzyl monoaza-27-crown-9
• Synonyms: N-benzyl monoaza-27-crown-9
• CAS NO: 922527-86-4
• Molecular Weight: 485.618
• Mol File: 922527-86-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: N-benzyl monoaza-27-crown-9(CAS DataBase Reference)
• NIST Chemistry Reference: N-benzyl monoaza-27-crown-9(922527-86-4)
• EPA Substance Registry System: N-benzyl monoaza-27-crown-9(922527-86-4)

Safety Data

• Hazardous Substances Data: 922527-86-4(Hazardous Substances Data)

Upstream product

• 105891-53-0 1-((2-(2-(2-(2-(2-(2-(2-(benzyloxy)ethoxy)ethoxy)ethoxy)ethoxy)ethoxy)ethoxy)ethoxy)methyl)benzene 
• 101-32-6 N-benzyl-diethanolamine 
• 69502-27-8 2-[2-[2-[2-[2-[2-[2-(p-tolylsulfonyloxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethyl 4-methylbenzenesulfonate 

Relevant articles and documents

Effect of crown ether ring size on binding and fluorescence response to saxitoxin in anthracylmethyl monoazacrown ether chemosensors

Convenient macrocyclization synthetic routes for the preparation of different-sized monoaza anthracylmethyl crown ether chemosensors (15-crown-5, 18-crown-6, 21-crown-7, 24-crown-8, and 27-crown-9) are described. Evaluation of these crowns as chemosensors for saxitoxin revealed that the larger crowns have moderately higher binding constants, with the 27-crown-9 chemosensor having the largest binding constant (2.29 × 105 (mol/L)-1). Fluorescence enhancements of 100% were observed at saxitoxin concentrations of 5 μmol/L, which is close to the detection limit in mouse bioassay.