922552-53-2 Usage
Description
(2-bromo-5-chlorophenyl)hydrazine is an organic compound that features a hydrazine group attached to a substituted phenyl ring. This molecule is characterized by the presence of both a bromine and a chlorine atom on the phenyl ring, which can be utilized for various synthetic applications in organic chemistry.
Uses
Used in Pharmaceutical Synthesis:
(2-bromo-5-chlorophenyl)hydrazine is used as a reactant/reagent in the synthetic preparation of tryptamine derivatives. Its unique structure allows for the formation of these biologically active compounds, which have potential applications in medicine.
Used in Organic Synthesis:
The bromine atom in (2-bromo-5-chlorophenyl)hydrazine can be employed as a protecting group during organic synthesis. This feature is particularly useful in the synthesis of complex organic molecules, where selective protection and deprotection of functional groups are necessary.
Used in Antiviral Drug Development:
(2-bromo-5-chlorophenyl)hydrazine is also used for the preparation of amides of amino acids and their analogs, which have potential antiviral properties. The presence of the halogenated phenyl ring may contribute to the antiviral activity of these compounds, making them valuable candidates for further research and development in the pharmaceutical industry.
Check Digit Verification of cas no
The CAS Registry Mumber 922552-53-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 9,2,2,5,5 and 2 respectively; the second part has 2 digits, 5 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 922552-53:
(8*9)+(7*2)+(6*2)+(5*5)+(4*5)+(3*2)+(2*5)+(1*3)=162
162 % 10 = 2
So 922552-53-2 is a valid CAS Registry Number.
922552-53-2Relevant articles and documents
Syntheses of 4-, 5-, 6-, and 7-substituted tryptamine derivatives and the use of a bromine atom as a protecting group
René, Olivier,Fauber, Benjamin P.
supporting information, p. 830 - 833 (2014/02/14)
Orthogonal syntheses of 4-, 5-, 6-, and 7-chloro substituted tryptamine derivatives were performed under the Grandberg-Zuyanova-modified Fisher indole-synthesis conditions. In the 4- and 6-substituted tryptamine cases, a bromine atom was utilized as an easily cleavable protecting group, which allowed complete regiocontrol. In addition, a chlorine substituent was preserved in the debromination step and could be utilized as a synthetic handle for late-stage diversification under modern Pd(0) catalysis conditions.
