92297-66-0

Basic information

• Product Name: Naphthalene, 2-methoxy-6-(1-methylethyl)- (9CI)
• Synonyms: Naphthalene, 2-methoxy-6-(1-methylethyl)- (9CI);2-methoxy-6-(1-methylethyl)naphthalene;2-Isopropyl-6-methoxynaphthalene
• CAS NO: 92297-66-0
• Molecular Formula: C₁₄H₁₆O
• Molecular Weight: 200.27624
• Product Categories: NAPHTALENE
• Mol File: 92297-66-0.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 305.4°Cat760mmHg
• Flash Point: 119.1°C
• Appearance: /
• Density: 1.013g/cm³
• Vapor Pressure: 0.00148mmHg at 25°C
• Refractive Index: 1.571
• Storage Temp.: 2-8°C
• CAS DataBase Reference: Naphthalene, 2-methoxy-6-(1-methylethyl)- (9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: Naphthalene, 2-methoxy-6-(1-methylethyl)- (9CI)(92297-66-0)
• EPA Substance Registry System: Naphthalene, 2-methoxy-6-(1-methylethyl)- (9CI)(92297-66-0)

Safety Data

• Hazardous Substances Data: 92297-66-0(Hazardous Substances Data)

Usage

InChI:InChI=1/C14H16O/c1-10(2)11-4-5-13-9-14(15-3)7-6-12(13)8-11/h4-10H,1-3H3

Upstream product

• 27602-75-1 2-(6-methoxy-2-naphthyl)propanal 
• 128333-18-6 1,2-Dihydro-4-methoxy-1-(3-methylbut-1-en-2-yl)benzocyclobutene 
• 159990-32-6 (S)-2-(6-methoxy-2-naphthyl)-1,2-propanediol 
• 34352-92-6 2-methoxy-6-(prop-1-en-2-yl)-naphthalene 
• 56437-05-9 1-cyano-4-methoxybenzocyclobutane 
• 60100-19-8 4-methoxybenzocyclobutene-1-carboxylic acid 
• 128333-11-9 Isopropyl 1,2-dihydro-4-methoxybenzocyclobuten-1-yl ketone 
• 3900-45-6 6-methoxy-2-acetylnaphthalene 
• 88407-85-6 3-(6-methoxy-naphthalen-2-yl)-3-methyl-oxiranecarboxylic acid ethyl ester 
• 91909-30-7 2-hydroxy-6-(1-methylethyl)naphthalene 
• 77-78-1 dimethyl sulfate 
• 67-56-1 methanol 
• 24157-81-1 2,6-diisopropylnaphthalene 

Downstream Products

• 3900-45-6 6-methoxy-2-acetylnaphthalene 
• 37414-52-1 2-(6-methoxy-2-naphthyl)-propyl alcohol 
• 27602-75-1 2-(6-methoxy-2-naphthyl)propanal 
• 23981-80-8 naproxen 
• 34352-83-5 2-methoxy-6-(1-hydroxy-1-methylethyl)naphthalene 

Relevant articles and documents

C -Glycosylation of Substituted β-Naphthols with Trichloroacetimidate Glycosyl Donors

Several glycosyl donors have been systematically investigated for C-glycosylation of substituted β-naphthols to delineate the effect of the substituents. Whereas glycosylations of the parent 2-naphthol are smoothly achievable, those of differently substituted 2-naphthols are cumbersome. Efficiency of the glycosylation depends on the nature of both the glycosyl donors and the substituents of the arene ring. Among various glycosyl donors, trichloroacetimidate glycosyl donors are found to be superior for glycosylation with substituted 2-naphthols.

A modification of the asymmetric dihydroxylation approach to the synthesis of (S)-2-arylpropanoic acids

Catalytic hydrogenolysis of (S)-2-phenyl-1-2-propanediol (2), prepared by an asymmetric dihydroxylation of α-methylstyrene (1) with AD-mix-α, over Pearlman's catalyst gave (S)-2-phenyl-1-propanol (3). This method was applied to the synthesis of optically active 2-arylpropanoic acid antiinflammatory agents, (S)-ibuprofen (8) and (S)-naproxen (13).

Synthesis of 2,6-Disubstituted Dihydronaphthalenes and Naphthalenes by Electrocyclic Reaction of o-Quinodimethane. A Synthesis of (+/-)-Naproxen

A survey of the electrocyclic reactions of o-quinodimethanes generated in situ by the thermolysis of dihydrobenzocyclobutenes with a variety of olefinic substituents at C-1 is reported.These reactions provide convenient access to the 2,6-disubstituted dihydronaphthalenes (11) and the naphthalenes (12).Thermolysis of the benzocyclobutenes (10) at 180 deg C in the presence of manganese dioxide affords in good yields the 2,6-di- and 2,3,6-tri-substituted naphthalenes (12) and (16).The naphthalenes (12b,f,h) thus obtained were easily converted into (+/-)-naproxen (5).