923-28-4

Basic information

• Product Name: N-AMYL ISOPROPYL KETONE
• Synonyms: 2-methyloctan-3-one;3-Octanone,2-methyl-;Isopropyl pentyl ketone;2-Methyl-3-Octanone,~97%;Isopropyl-N-pentylketone;Pentylisopropyl ketone;AMYL ISOPROPYL KETONE;2-METHYL-3-OCTANONE
• CAS NO: 923-28-4
• Molecular Formula: C₉H₁₈O
• Molecular Weight: 142.24
• EINECS: 213-092-4
• Mol File: 923-28-4.mol
• Article Data: 16

Chemical Properties

• Melting Point: -18.52°C (estimate)
• Boiling Point: 182.85°C
• Flash Point: 59.1°C
• Appearance: /
• Density: 0.8258 (estimate)
• Vapor Pressure: 0.809mmHg at 25°C
• Refractive Index: 1.4202 (estimate)
• CAS DataBase Reference: N-AMYL ISOPROPYL KETONE(CAS DataBase Reference)
• NIST Chemistry Reference: N-AMYL ISOPROPYL KETONE(923-28-4)
• EPA Substance Registry System: N-AMYL ISOPROPYL KETONE(923-28-4)

Safety Data

• Hazardous Substances Data: 923-28-4(Hazardous Substances Data)

Usage

InChI:InChI=1/C9H18O/c1-4-5-6-7-9(10)8(2)3/h8H,4-7H2,1-3H3

Upstream product

• 64-18-6 formic acid 
• 6974-84-1 2,3-epoxy-3-methyl-2-pentyl-butyric acid ethyl ester 
• 26533-34-6 isopropyl amyl carbinol 
• 38614-18-5 isopropylzinc iodide 
• 142-61-0 Hexanoyl chloride 
• 71-43-2 benzene 
• 79-31-2 isobutyric Acid 
• 142-62-1 hexanoic acid 
• 542-69-8 1-iodo-butane 
• 39139-90-7 N-(3-methyl-2-butylidene)cyclohexylamine 
• 1518-06-5 1,3-dibromo-3-methyl-2-butanone 
• 693-25-4 n-pentylmagnesium bromide 
• 78-84-2 isobutyraldehyde 
• 2863-47-0 1-methanesulfinyl-heptan-2-one 

Downstream Products

• 26533-34-6 isopropyl amyl carbinol 

Relevant articles and documents

C-H Alkylation of Aldehydes by Merging TBADT Hydrogen Atom Transfer with Nickel Catalysis

Catalyst controlled site-selective C-H functionalization is a challenging but powerful tool in organic synthesis. Polarity-matched and sterically controlled hydrogen atom transfer (HAT) provides an excellent opportunity for site-selective functionalization. As such, the dual Ni/photoredox system was successfully employed to generate acyl radicals from aldehydes via selective formyl C-H activation and subsequently cross-coupled to generate ketones, a ubiquitous structural motif present in the vast majority of natural and bioactive molecules. However, only a handful of examples that are constrained to the use of aryl halides are developed. Given the wide availability of amines, we developed a cross-coupling reaction via C-N bond cleavage using the economic nickel and TBADT catalyst for the first time. A range of alkyl and aryl aldehydes were cross-coupled with benzylic and allylic pyridinium salts to afford ketones with a broad spectrum of functional group tolerance. High regioselectivity toward formyl C-H bonds even in the presence of α-methylene carbonyl or α-amino/oxy methylene was obtained.

A Ruthenium-Grafted Hydrotalcite as a Multifunctional Catalyst for Direct α-Alkylation of Nitriles with Primary Alcohols

Treatment of a hydrotacite, Mg6Al2(OH)16CO3, with an aqueous solution of RuCl3·nH2O afforded a monomeric Ru(IV) species on the surface of the hydrotalcite. This novel Ru-grafted hydrotalcite (Ru/HT) efficiently catalyzed α-alkylation of nitriles with primary alcohols through the cooperative catalysis between the Ru species and the surface base sites. The catalyst system could be further extended for the one-pot synthesis of α,α-dialkylated phenylacetonitriles via the base-catalyzed Michael reaction of α-alkylated phenylacetonitrile with activate olefins. Copyright

Development of new iron catalysts for the tandem isomerization-aldol condensation of allylic alcohols

(bda)Fe(CO)3 and (COT)Fe(CO)3 are shown to be excellent catalysts for the tandem isomerization-aldol reaction of allylic alcohols with aldehydes and to significantly increase the scope of this aldolization process, especially, in the