923012-48-0Relevant articles and documents
The synthesis of three new heterocycles: the pyrido[4,3 or 3,4 or 2,3-c]-1,5-naphthyridines
Cailly, Thomas,Fabis, Frédéric,Legay, Rémi,Oulyadi, Hassan,Rault, Sylvain
, p. 71 - 76 (2007/10/03)
Pyrido[4,3 or 3,4 or 2,3-c]-1,5-naphthyridines were obtained with good yields after chlorodehydroxylation and dehalogenation reactions starting from the parent pyridonaphthyridinones. These pyridonaphthyridinones were synthesized in a two-step procedure using a Suzuki cross-coupling reaction between 2-chloro-3-fluoropyridine and orthocyanopyridylboronic esters followed by a KOH-mediated anionic ring closure.