92352-24-4

Basic information

• Product Name: 3-(2-FURYL)-1H-PYRAZOLE-5-CARBOHYDRAZIDE
• Synonyms: 3-(2-FURYL)-1H-PYRAZOLE-5-CARBOHYDRAZIDE;AKOS BBS-00002713;3-(Furan-2-yl)-1H-pyrazole-5-carbohydrazide;5-(Furan-2-yl)-1H-pyrazole-3-carbohydrazide;5-(2-furyl)-1H-pyrazole-3-carbohydrazide;5-Furan-2-yl-2H-pyrazole-3-carboxylic acid, hydrazide
• CAS NO: 92352-24-4
• Molecular Formula: C₈H₈N₄O₂
• Molecular Weight: 192.17
• Mol File: 92352-24-4.mol
• Article Data: 2

Chemical Properties

• Melting Point: 195-196 °C
• Appearance: /
• Density: 1.407±0.06 g/cm3(Predicted)
• PKA: 11.50±0.10(Predicted)
• CAS DataBase Reference: 3-(2-FURYL)-1H-PYRAZOLE-5-CARBOHYDRAZIDE(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(2-FURYL)-1H-PYRAZOLE-5-CARBOHYDRAZIDE(92352-24-4)
• EPA Substance Registry System: 3-(2-FURYL)-1H-PYRAZOLE-5-CARBOHYDRAZIDE(92352-24-4)

Safety Data

• Statements: 36/37/38
• Safety Statements: 26-36/37/39
• HazardClass: IRRITANT
• Hazardous Substances Data: 92352-24-4(Hazardous Substances Data)

Usage

Chemical Properties

White solid

Upstream product

• 36983-35-4 ethyl 4-(furan-2-yl)-2,4-dioxobutyrate 
• 64-17-5 ethanol 
• 7803-57-8 hydrazine hydrate 
• 1192-62-7 1-(2-furyl)-1-ethanone 
• 374063-90-8 methyl 4-(furan-2-yl)-2,4-dioxobutanoate 
• 1186021-68-0 3-(2-furan-2-yl-2-oxoethyl)-2H-[1,2,4]triazino-[2,3-c]quinazolin-2-one 
• 34020-22-9 ethyl 5-(furan-2-yl)-1H-pyrazole-3-carboxylate 

Relevant articles and documents

Synthesis, characterization, and bioassay of a new class of pyrazolyl/isoxazolyl oxadiazoles

Abstract: This study aimed at describing a simple and facile synthesis of pyrazolyl/isoxazolyl 1,3,4-oxadiazole derivatives from the synthetic intermediates pyrazolyl/isoxazolyl carboxylates adopting conventional and ultrasound irradiation methods. In fact ultrasound-promoted synthesis led to the formation of title compounds in higher yields and in shorter reaction times when compared with conventional methods. All the compounds were characterized by IR, 1H NMR, 13C NMR, and mass spectra. The synthesized compounds were evaluated for their antioxidant and anti-inflammatory activities. The bioassay results indicated that some title compounds were found to be more potent than standard drugs. Amongst all the tested compounds furanyl/pyridinyl linked pyrazolyl/isoxazolyl methoxyphenylsulfonylmethyloxadiazoles were identified as potential antioxidant and anti-inflammatory agents. Graphical abstract: [Figure not available: see fulltext.].