92445-49-3Relevant articles and documents
Anodic Oxidation of Aminotetrazoles: A Mild and Safe Route to Isocyanides
Leech, Matthew C.,Petti, Alessia,Tanbouza, Nour,Mastrodonato, Andrea,Goodall, Iain C. A.,Ollevier, Thierry,Dobbs, Adrian P.,Lam, Kevin
supporting information, p. 9371 - 9375 (2021/12/09)
A new electrochemical method for the preparation of isocyanides from easily accessible aminotetrazole derivatives has been developed, which tolerates an unprecedented range of functional groups. The use of chemical, rather than electrochemical, oxidation to afford isocyanides was also demonstrated, which provides access to these compounds for those without electrosynthesis equipment. The practicality of scale-up using flow electrochemistry has been demonstrated, in addition to the possibility of using electrochemically generated isocyanides in further reactions.
STUDIES ON ISONITRILES AND RELATED COMPOUNDS. SYNTHESIS OF 1H-PYRROLE AND 1H-IMIDAZOLE DERIVATIVES VIA 1,3-DIPOLAR CYCLOADDITION
Bossio, Ricardo,Marcaccini, Stefano,Paoli, Paola,Pepino, Roberto,Polo, Cecilia
, p. 1855 - 1860 (2007/10/02)
4-Nitrobenzyl isocyanide (1) reacted with arylsulfenyl chlorides (2) to give isothiocarbamoyl chlorides (3).Treatment of 3 with NEt3 afforded nitrile ylides (4) which reacted with stoichiometric amounts of dimethyl acetylenedicarboxylate to give 1H-pyrrol