92447-15-9

Basic information

• Product Name: Thymidine, 4-O-phenyl-
• CAS NO: 92447-15-9
• Molecular Formula: C16H18N2O5
• Molecular Weight: 318.329
• Mol File: 92447-15-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: Thymidine, 4-O-phenyl-(CAS DataBase Reference)
• NIST Chemistry Reference: Thymidine, 4-O-phenyl-(92447-15-9)
• EPA Substance Registry System: Thymidine, 4-O-phenyl-(92447-15-9)

Safety Data

• Hazardous Substances Data: 92447-15-9(Hazardous Substances Data)

Upstream product

• 92447-13-7 Methoxy-acetic acid (2R,3S,5R)-2-(2-methoxy-acetoxymethyl)-5-(5-methyl-2-oxo-4-[1,2,4]triazol-1-yl-2H-pyrimidin-1-yl)-tetrahydro-furan-3-yl ester 
• 92447-12-6 3',5'-di-O-methoxyacetylthymidine 
• 92447-14-8 Methoxy-acetic acid (2R,3S,5R)-2-(2-methoxy-acetoxymethyl)-5-(5-methyl-2-oxo-4-phenoxy-2H-pyrimidin-1-yl)-tetrahydro-furan-3-yl ester 

Downstream Products

• 50-89-5 thymidine 
• 36792-88-8 2-deoxy-D-ribose 
• 6979-97-1 3',5'-diacetylthymidine 
• 92447-16-0 4-O-phenyl-5'-O-(9-phenyl-9H-xanthen-9-yl)thymidine 

Relevant articles and documents

The Protection of Thymine and Guanine Residues in Oligodeoxyribonucleotide Synthesis

Thymidine is converted in four steps into its crystalline 4-O-phenyl derivative (14b) in 72percent overall yield. 2'-Deoxyguanosine is converted in five steps into its 6-O-(2-nitrophenyl)-2-N-phenylacetyl and crystalline 6-O-(3,5-dichlorophenyl)-2-N-phenylacetyl derivatives in ca. 39 and 42percent overall yields, respectively.Compounds (14b), (19a), and (19b) are converted into the corresponding crystalline 5'-O-(9-phenyl-9H-xanthen-9-yl) derivatives (15), (20a), and (20b), respectively.The actions of N1,N1,N3,N3-tetramethylguanidinium 2-nitrobenzaldehyde oximate, 80percent acetic acid, potassium carbonate in aqueous dioxane, pyridine, and triethylammonium toluene-p-thiolate on (14b), (19a), and (19b) have been investigated.