92487-21-3

Basic information

• Product Name: N'-((1H-indol-3-yl)methylene)-4-methylbenzenesulfonohydrazide
• Synonyms: N'-((1H-indol-3-yl)methylene)-4-methylbenzenesulfonohydrazide
• CAS NO: 92487-21-3
• Molecular Weight: 313.38
• Mol File: 92487-21-3.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: N'-((1H-indol-3-yl)methylene)-4-methylbenzenesulfonohydrazide(CAS DataBase Reference)
• NIST Chemistry Reference: N'-((1H-indol-3-yl)methylene)-4-methylbenzenesulfonohydrazide(92487-21-3)
• EPA Substance Registry System: N'-((1H-indol-3-yl)methylene)-4-methylbenzenesulfonohydrazide(92487-21-3)

Safety Data

• Hazardous Substances Data: 92487-21-3(Hazardous Substances Data)

Upstream product

• 98-59-9 p-toluenesulfonyl chloride 
• 487-89-8 Indole-3-carboxaldehyde 
• 1576-35-8 toluene-4-sulfonic acid hydrazide 
• 120-72-9 indole 

Downstream Products

• 1968-05-4 3,3'-diindolylmethane 

Relevant articles and documents

CuI-catalyzed highly regioselective C[sbnd]H functionalization of indoles using indole-3-tosylhydrazones as carbene precursor: An efficient synthesis of 3,3-bis(indolyl)methane derivatives

Herein, we have developed a novel approach for synthesizing symmetrical and unsymmetrical 3,3-bis(indolyl)methane derivatives via CuI-catalyzed C[sbnd]H functionalization of indole using indole-3-tosylhydrazones as carbene precursor. This procedure works well with different substitutions such as NO2, Br, CH3 and OMe on indole or indole-3-tosylhydrazones and features high regioselectivity for C-3 functionalization over the C-1 and N-1 positions. Further, we have also revealed the feasibility of this protocol in a one-pot fashion starting from indole-3-carboxyaldehyde.

Synthesis of heterocycle-attached methylidenebenzenesulfonohydrazones as antifungal agents

A series of heterocycle-attached methylidenebenzenesulfonohydrazone derivatives were synthesized and evaluated for their antifungal activities against seven phytopathogenic fungi such as Fusarium graminearum, Alternaria solani, Valsa Mali, Phytophthora ca

Synthesis, anti-inflammatory and analgesic activity evaluation of some amidine and hydrazone derivatives

A number of amidine derivatives (3a-i) were synthesized by condensation of cyanopyridine and cyanopyrazine with sulfonylhydrazides in the presence of sodium methoxide. 2-Acetylpyridine and 4-acetylpyridine were condensed with sulfonylhydrazides by microwa