925462-42-6

Basic information

• Product Name: 3-Butyn-2-one, 1-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-4-phenyl-
• CAS NO: 925462-42-6
• Molecular Formula: C16H22O2Si
• Molecular Weight: 274.435
• Mol File: 925462-42-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 3-Butyn-2-one, 1-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-4-phenyl-(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Butyn-2-one, 1-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-4-phenyl-(925462-42-6)
• EPA Substance Registry System: 3-Butyn-2-one, 1-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-4-phenyl-(925462-42-6)

Safety Data

• Hazardous Substances Data: 925462-42-6(Hazardous Substances Data)

Upstream product

• 67226-78-2 ethyl 2-(tert-butyldimethylsilyloxy)acetate 
• 18162-48-6 tert-butyldimethylsilyl chloride 

Downstream Products

• 925462-08-4 carbonic acid allyl ester 1-(tert-butyl-dimethyl-silanyloxymethylene)-3-phenyl-prop-2-ynyl 
• 1219685-01-4 C₁₀H₈O₂ 

Relevant articles and documents

Enantioselective synthesis of α-tertiary hydroxyaldehydes by palladium-catalyzed asymmetric allylic alkylation of enolates

Chiral α-tertiary hydroxyaldehydes are very versatile building blocks in synthetic chemistry. Herein, we report the first examples of a catalytic asymmetric protocol for the synthesis of such compounds from readily available α-halo or α-hydroxy ketones or enol silyl ethers with excellent yields and enantioselectivity. Its synthetic utility is demonstrated in the short, efficient formal synthesis of (S)-oxybutynin. In this process, the chiral ligand controls the regioselectivity as well as the enantioselectivity. Copyright