92569-86-3

Basic information

• Product Name: 2-Propenal, 3-(5-bromo-2-hydroxyphenyl)-
• CAS NO: 92569-86-3
• Molecular Formula: C9H7BrO2
• Molecular Weight: 227.057
• Mol File: 92569-86-3.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: 2-Propenal, 3-(5-bromo-2-hydroxyphenyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Propenal, 3-(5-bromo-2-hydroxyphenyl)-(92569-86-3)
• EPA Substance Registry System: 2-Propenal, 3-(5-bromo-2-hydroxyphenyl)-(92569-86-3)

Safety Data

• Hazardous Substances Data: 92569-86-3(Hazardous Substances Data)

Upstream product

• 75-07-0 acetaldehyde 
• 1761-61-1 5-bromosalicyclaldehyde 
• 2136-75-6 (triphenylphosphoranylidene)acetaldehyde 
• 22532-62-3 4-bromosalicylaldehyde 

Downstream Products

• 19063-55-9 6-bromo-2H-chromen-2-one 
• 20921-00-0 6-bromo-3,4-dihydro-2H-1-benzopyran-2-one 

Relevant articles and documents

Kinetic Resolution and Dynamic Kinetic Resolution of Chromene by Rhodium-Catalyzed Asymmetric Hydroarylation

A highly efficient kinetic resolution and dynamic kinetic resolution of chromene is reported for the first time and they procced by a rhodium-catalyzed asymmetric hydroarylation pathway. This new approach offers versatile access to various chiral 2,3-diaryl-chromanes containing vicinal stereogenic centers, as well as the recovered chiral flavenes, in high yields with excellent ee values (s factor up to 532). Particularly noteworthy is that this strategy can be further extended to the establishment of a dynamic version of the kinetic resolution of chromene acetals and allows complete access to chiral isoflavanes and α-aryl hydrocoumarins.

Bi(OTf)3-catalyzed addition of isocyanides to 2: H -chromene acetals: An efficient pathway for accessing 2-carboxamide-2 H -chromenes

Bismuth triflate (Bi(OTf)3) is identified as an efficient catalyst for the direct addition of isocyanides to 2H-chromene acetals. The large scope of isocyanides and chromene acetals makes them suitable substrates in this catalytic system. By this synthetic strategy, a polyfunctional molecular scaffold, 2-carboxamide-2H-chromenes could be prepared efficiently in one step up to 95% yield. In addition, this efficient and practical protocol proceeded smoothly in the gram scale even when the catalytic loading was reduced to 2 mol%.

INTRAMOLECULAR CYCLIZATION OF 2-HYDROXYCINNAMALDEHYDES

The effect of substituents on the intramolecular cyclization of 2-hydroxycinnamaldehydes was studied.It was established that aldehydes that contain bulky groups in the side chain and in the 3 position of the benzene ring are readily converted to intramole