92576-55-1

Basic information

• Product Name: cis (+/-)-4-phenyl-5-dichloroacetamido-1,3-dioxane
• CAS NO: 92576-55-1
• Molecular Weight: 290.146
• Mol File: 92576-55-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: cis (+/-)-4-phenyl-5-dichloroacetamido-1,3-dioxane(CAS DataBase Reference)
• NIST Chemistry Reference: cis (+/-)-4-phenyl-5-dichloroacetamido-1,3-dioxane(92576-55-1)
• EPA Substance Registry System: cis (+/-)-4-phenyl-5-dichloroacetamido-1,3-dioxane(92576-55-1)

Safety Data

• Hazardous Substances Data: 92576-55-1(Hazardous Substances Data)

Upstream product

• 79-36-7 dichloroacethyl chloride 
• 78021-92-8 4-phenyl-5-amino-1,3-dioxane 

Downstream Products

• 92695-77-7 cis (+/-)-4-p-nitrophenyl-5-dichloroacetamido-1,3-dioxane 
• 126482-97-1 2,2-Dichloro-N-[(4S,5S)-4-(2-nitro-phenyl)-[1,3]dioxan-5-yl]-acetamide 
• 126065-71-2 2,2-Dichloro-N-[(4S,5S)-4-(3-nitro-phenyl)-[1,3]dioxan-5-yl]-acetamide 
• 126065-72-3 threo (+/-)-1-(acetoxymethoxy)-3-acetoxy-2-dichloroacetamido-1-p-nitrophenylpropane 
• 56-75-7 threo (+/-)-2,2-dichloro-N-<2-hydroxy-1-(hydroxymethyl)-2-(4-nitrophenyl)ethyl> acetamide 
• 126065-73-4 Acetic acid (2-dichloromethyl-4,5-dihydro-oxazol-4-yl)-(4-nitro-phenyl)-methoxymethyl ester 

Relevant articles and documents

REGIOSELECTIVE ACYLATIVE CLEAVAGE OF CYCLIC FORMAL OF CHLORAMPHENICOL

The amide 6 has been synthesised by reacting the amine 3 with dichloroketene in situ.This amide 6 on nitration gave formal 7, which when reacted with acetic anhydride and p-toluene sulfonic acid underwent regioselective cleavage of the dioxane ring to furnish the hemiacetal 11.This on treatment with methanol-water-ammonia yielded chloramphenicol 2.