92631-27-1

Basic information

• Product Name: 6-p-tolylhex-1-en-5-ol
• Synonyms: 6-p-tolylhex-1-en-5-ol
• CAS NO: 92631-27-1
• Molecular Weight: 190.285
• Mol File: 92631-27-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 6-p-tolylhex-1-en-5-ol(CAS DataBase Reference)
• NIST Chemistry Reference: 6-p-tolylhex-1-en-5-ol(92631-27-1)
• EPA Substance Registry System: 6-p-tolylhex-1-en-5-ol(92631-27-1)

Safety Data

• Hazardous Substances Data: 92631-27-1(Hazardous Substances Data)

Upstream product

• 104-09-6 4-methylphenylacetaldehyde 
• 7103-09-5 4-but-1-enylmagnesium bromide 

Downstream Products

• 92631-28-2 1-(4-methylphenyl)-5-hexen-2-one 
• 70855-13-9 1-(4-methylphenyl)-hexane-2,5-dione 
• 92631-30-6 2-trimethylsilyloxy-1-p-tolylhexa-1,5-diene 
• 92631-29-3 5-chloro-6-phenylthio-1-p-tolylhexan-2-one 
• 92631-31-7 5-phenylthiomethyl-2tetrahydrofuran 
• 92631-32-8 5-chloro-1,6-bis(phenylthio)-1-p-tolylhexan-2-one 

Relevant articles and documents

Synthetic Studies on Aromatic Sesquiterpenoids: Synthesis of Curcumene Ether by Olefin Cyclisation

The acid-catalysed cyclisation of the olefinic β-hydroxy sulphides (15a) and (15b) gave 3-phenylthiocurcumene ether as a diastereoisomeric mixture together with 5,5-dimethyl-4-phenylthio-1-p-tolylcyclohex-1-ene (16) and 2-methyl-3-(1-methyl-1-phenylthioethyl)-2-p-tolylcyclobutan-1-ol (19).The diastereoisomers (17) and (18) were converted into curcumene ether (24).Treatment of the silyl enol ether (7) with benzenesulphenyl chloride yielded 5-phenylthiomethyl-2-tetrahydrofuran (8) and 5-chloro-1,6-bis(phenylthio)-1-p-tolylhexan-2-one (9). 1-p-Tolylhexane-2,5-dione (10) was also synthesised from (5) employing a palladium-catalysed oxidation, and this result constitutes a formal total synthesis of cuparene (11).