92689-49-1 Usage
Uses
Annamycin is used as a Topoisomerase II inhibitor, during apoptosis induction in cancer research for anti-tumor activity.
Check Digit Verification of cas no
The CAS Registry Mumber 92689-49-1 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 9,2,6,8 and 9 respectively; the second part has 2 digits, 4 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 92689-49:
(7*9)+(6*2)+(5*6)+(4*8)+(3*9)+(2*4)+(1*9)=181
181 % 10 = 1
So 92689-49-1 is a valid CAS Registry Number.
InChI:InChI=1/C26H25IO11/c1-9-19(30)24(35)18(27)25(37-9)38-13-7-26(36,14(29)8-28)6-12-15(13)23(34)17-16(22(12)33)20(31)10-4-2-3-5-11(10)21(17)32/h2-5,9,13,18-19,24-25,28,30,33-36H,6-8H2,1H3/t9-,13-,18+,19-,24-,25-,26-/m0/s1
92689-49-1Relevant articles and documents
Synthesis of 4-demethoxyadriamycinone utilizing ruthenium-catalyzed oxidation of allyl acetates
Hottop, Torsten,Gutke, Hans-Jürgen,Murahashi, Shun-Ichi
, p. 3343 - 3346 (2007/10/03)
A new method for the construction of the side chain of anti-cancer drugs adriamycins is demonstrated by the synthesis of 4-demethoxyadriamycinone. The key step is the ruthenium-catalyzed oxidation of allyl acetates to the corresponding α-hydroxyketones.