927-67-3

Basic information

• Product Name: N-PROPYLTHIOUREA
• Synonyms: 1-PROPYL-2-THIOUREA;N-PROPYLTHIOUREA;PROPYLTHIOUREA;Thiourea, propyl-;propyl-2-thiourea;PROPYLTHIOHARNSTOFF PESTANAL Packung;1-N-PROPYLTHIOUREA;1-Propylthiourea
• CAS NO: 927-67-3
• Molecular Formula: C₄H₁₀N₂S
• Molecular Weight: 118.2
• EINECS: 213-158-2
• Product Categories: Alpha sort;N-PAlphabetic;P;Pesticides&Metabolites;PON - PT
• Mol File: 927-67-3.mol
• Article Data: 6

Chemical Properties

• Melting Point: 120 °C
• Boiling Point: 101°C 1mm
• Flash Point: 63.9 °C
• Appearance: /
• Density: 1.054 g/cm³
• Vapor Pressure: 0.825mmHg at 25°C
• Refractive Index: 1.537
• PKA: 14.83±0.29(Predicted)
• BRN: 1743064
• CAS DataBase Reference: N-PROPYLTHIOUREA(CAS DataBase Reference)
• NIST Chemistry Reference: N-PROPYLTHIOUREA(927-67-3)
• EPA Substance Registry System: N-PROPYLTHIOUREA(927-67-3)

Safety Data

• Hazard Codes: Xn
• Statements: 20/21/22-22
• Safety Statements: 22-36/37/39
• RIDADR: 2811
• HazardClass: 6.1
• PackingGroup: III
• Hazardous Substances Data: 927-67-3(Hazardous Substances Data)

Usage

Uses

Metal Scavenger: Pd, Pt, Rh, Ru, and Hg

InChI:InChI=1/C4H10N2S/c1-2-3-6-4(5)7/h2-3H2,1H3,(H3,5,6,7)

Upstream product

• 107-10-8 propylamine 
• 625-57-0 O-ethyl thiocarbamate 
• 628-30-8 n-Propyl isothiocyanate 
• 14326-98-8 N-tert-butyl-N'-propyl-thiourea 
• 29337-33-5 N-(n-propyl)-N'-benzoylthiourea 
• 137526-99-9 1-Methyl-3-{5-[(E)-propylimino]-4-p-tolyl-4,5-dihydro-[1,2,4]thiadiazol-3-yl}-thiourea 
• 137527-00-5 1-Ethyl-3-{5-[(E)-propylimino]-4-p-tolyl-4,5-dihydro-[1,2,4]thiadiazol-3-yl}-thiourea 
• 137526-95-5 1-Methyl-3-{4-phenyl-5-[(E)-propylimino]-4,5-dihydro-[1,2,4]thiadiazol-3-yl}-thiourea 

Downstream Products

• 95167-48-9 4-amino-5-phenyl-3-propyl-3H-thiazol-2-ylideneamine 
• 145012-93-7 N-(tert-butoxycarbonyl)-N’-(propyl)thiourea 
• 1148118-59-5 6-phenyl-5-[2''-hydroxynaphthyl-(1'')-methyl]-1-propyl-2-thioxo-2,3-dihydro-1H-pyrimidin-4-one 
• 1202276-21-8 5-(8-phenyl-[1,2,4]triazolo[4,3-a]pyridin-6-yl)-N-propylthiazol-2-amine 
• 200938-58-5 6-iodo-3-propyl-2-thioxo-2,3-dihydroquinazolin-4(1H)-one 

Relevant articles and documents

Novel (E)-1-(4-methyl-2-(alkylamino)thiazol-5-yl)-3-arylprop-2-en-1-ones as potent antimicrobial agents

New (E)-1-(4-methyl-2-(alkylamino)thiazol-5-yl)-3-arylprop-2-en-1-ones, unsubstituted or carrying fluoro, bromo, methoxy, nitro, methyl and chloro groups on the benzene ring, were synthesized and assayed in vitro for their antimicrobial activity against Gram positive and Gram negative bacteria and fungi. The compounds were very potent towards all tested microorganisms and in most cases their activity was better than that of reference drugs.

Synthesis and inhibitory effects of 1,4,5-trialkyl-2-thioimidazole derivatives on platelet aggregation

New 1,4,5-trialkyl-2-thioimidazole have been synthesized by the condensation of α-hydroxyketones and alkylthioureas. The in vitro platelet aggregation inhibiting effect of prepared compounds on human platelets was studied in the presence of ADP and collagen as inducers. The formation of thromboxane B2 (TXB2) was inhibited. 1-isopropyl-4,5-dimethyl-2-thioimidazole has the greatest aggregation inhibiting effect, about 4 times that of aspirin. It highly inhibits the production of TXB2 (68,5% for a final concentration of 0,04 M).

Reduction of 1,2,4-thiadiazol-3-yl-thioureas: Formation of 1,3,5-triazine-2-thiones, 2,4-dithiones and amidinothioureas

Reduction of thiadiazol-3-yl-thioureas (I) in alcoholic ammoniacal hydrogen sulphide furnish 1,3,5-triazine-2-thiones (III), 2,4-dithiones (VI) and/or amidinothioureas (VII) depending upon the substituents in I.