92756-13-3Relevant articles and documents
Synthesis of Some New Thiazolidinone and 2-Thiohydantoin Derivatives Bearing an Isatin Moiety
Mahmoud, A.M.,Abdel-Rahman, A.E.,El-Naggar, G.M.,El-Sherief, H.A.
, p. 379 - 381 (2007/10/02)
2-(Isatin-3-azino)-4-thiazolidinone (I) and 1-(isatin-3-imino)-2-thiohydantoin (III) have been obtained by condensation of isatin-3-thiosemicarbazone with chloroacetic acid under different conditions.Compounds I and III on interaction with aromatic or heterocyclic aldehydes afford 5-arylidene-2-(isatin-3-azino)thiazolidinones (II) and 5-arylidene-3-(isatin-3-imino)-2-thiohydantoins (IV) respectively.These compounds (II, IV) have been screened for their antimicrobial activities.