927800-61-1

Basic information

• Product Name: 3-BROMO-4-IODOQUINOLINE
• Synonyms: 3-BROMO-4-IODOQUINOLINE
• CAS NO: 927800-61-1
• Molecular Formula: C9H5BrIN
• Molecular Weight: 333.95
• Mol File: 927800-61-1.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 3-BROMO-4-IODOQUINOLINE(CAS DataBase Reference)
• NIST Chemistry Reference: 3-BROMO-4-IODOQUINOLINE(927800-61-1)
• EPA Substance Registry System: 3-BROMO-4-IODOQUINOLINE(927800-61-1)

Safety Data

• Hazardous Substances Data: 927800-61-1(Hazardous Substances Data)

Upstream product

• 529-37-3 4(1H)-quinolinone 
• 74575-17-0 3-bromo-4-chloroquinoline 
• 68158-36-1 3-bromoquinolin-4(1H)-one 
• 15568-92-0 5-(N-phenyl)-aminomethylene-2,2-dimethyl-1,3-dioxane-4,6-dione 
• 62-53-3 aniline 

Downstream Products

• 239-09-8 11H-indolo[3,2-c]quinoline 

Relevant articles and documents

A concise synthesis of indoloquinoline skeletons applying two consecutive Pd-catalyzed reactions

The indoloquinoline alkaloids cryptolepine (1), neocryptolepine (2), isocryptolepine (3), and isoneocryptolepine (4) are important tools in traditional medicine. Now, their precursors 1a-4a were synthesized in two steps starting from the corresponding bromo-iodoquinolines. Our strategy is based on palladium-catalyzed reactions, applying regioselective Buchwald-Hartwig amination on 2,3- and 3,4-dihaloquinolines followed by an intramolecular Heck-type reaction. Both steps were carried out under microwave irradiation.