927874-59-7

Basic information

• Product Name: N,N'-bis(benzyloxycarbonyl)-N-(2-hydroxy-1-hydroxymethyl-ethyl)-guanidine
• Synonyms: N,N'-bis(benzyloxycarbonyl)-N-(2-hydroxy-1-hydroxymethyl-ethyl)-guanidine
• CAS NO: 927874-59-7
• Molecular Weight: 401.419
• Mol File: 927874-59-7.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: N,N'-bis(benzyloxycarbonyl)-N-(2-hydroxy-1-hydroxymethyl-ethyl)-guanidine(CAS DataBase Reference)
• NIST Chemistry Reference: N,N'-bis(benzyloxycarbonyl)-N-(2-hydroxy-1-hydroxymethyl-ethyl)-guanidine(927874-59-7)
• EPA Substance Registry System: N,N'-bis(benzyloxycarbonyl)-N-(2-hydroxy-1-hydroxymethyl-ethyl)-guanidine(927874-59-7)

Safety Data

• Hazardous Substances Data: 927874-59-7(Hazardous Substances Data)

Upstream product

• 534-03-2 serinol 
• 152120-55-3 N,N-bis(benzyloxycarbonyl)-1H-pyrazole-1-carboxamidine 

Downstream Products

• 927874-60-0 N,N'-bis(benzyloxycarbonyl)-N-[2-(tert-butyl-dimethyl-silanyloxy)-1-(tert-butyl-dimethyl-silanyloxymethyl)-ethyl]-guanidine 
• 927874-60-0 N,N'-bis(benzyloxycarbonyl)-N''-[2-(tert-butyl-dimethyl-silanyloxy)-1-(tert-butyl-dimethyl-silanyloxymethyl)-ethyl]-guanidine 

Relevant articles and documents

PYRIMIDINES AND VARIANTS THEREOF, AND USES THEREFOR

The present disclosure provides pyrimidine compounds and uses thereof, for example, for the treatment of diseases associated with P2X purinergic receptors. In certain aspects, the present disclosure provides P2X3 and/or P2X2/3 antagonists which are useful, for example, for the treatment of visceral organ, cardiovascular and pain-related diseases, conditions and disorders.

Diaminopyrimidines as P2X3 and P2X2/3 modulators

Compounds of formula (I): wherein R1 and R2 are as defined herein. Also disclosed are methods of making and using the subject compounds.