927892-95-3

Basic information

• Product Name: 2-Pyridinone, 4-[(4-fluorophenyl)methoxy]-1,2-dihydro-1-[4-[[(methylsulfonyl)oxy]methyl ]phenyl]-
• CAS NO: 927892-95-3
• Molecular Formula: C20H18FNO5S
• Molecular Weight: 403.431
• Mol File: 927892-95-3.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 2-Pyridinone, 4-[(4-fluorophenyl)methoxy]-1,2-dihydro-1-[4-[[(methylsulfonyl)oxy]methyl ]phenyl]-(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Pyridinone, 4-[(4-fluorophenyl)methoxy]-1,2-dihydro-1-[4-[[(methylsulfonyl)oxy]methyl ]phenyl]-(927892-95-3)
• EPA Substance Registry System: 2-Pyridinone, 4-[(4-fluorophenyl)methoxy]-1,2-dihydro-1-[4-[[(methylsulfonyl)oxy]methyl ]phenyl]-(927892-95-3)

Safety Data

• Hazardous Substances Data: 927892-95-3(Hazardous Substances Data)

Upstream product

• 927892-94-2 4-[(4-fluorobenzyl)oxy]-1-[4-(hydroxymethyl)phenyl]pyridin-2(1H)-one 
• 124-63-0 methanesulfonyl chloride 

Downstream Products

• 927892-97-5 tert-butyl (2S)-2-[({4-[4-[(4-fluorobenzyl)oxy]-2-oxopyridin-1(2H)-yl]benzyl}oxy)methyl]pyrrolidine-1-carboxylate 
• 927892-96-4 (R)-tert-butyl 3-({4-[4-[(4-fluorobenzyl)oxy]-2-oxopyridin-1(2H)-yl]benzyl}oxy)pyrrolidine-1-carboxylate 
• 1189572-63-1 C₂₃H₂₃FN₂O₂ 

Relevant articles and documents

Discovery of novel phenethylpyridone derivatives as potent melanin-concentrating hormone 1 receptor antagonists

Novel phenethylpyridone derivatives were identified as potent human melanin-concentrating hormone 1 receptor (MCH-1R) antagonists. A search for surrogates for the 4-(2-aminoethoxy)phenyl moiety of 1 resulted in discovery of 2-[4-(aminomethyl)phenyl]ethyl substructure as in 6a. Successive optimization of the right-hand moiety led to the identification of a number of potent derivatives.